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Givinostat (ITF2357)

pharmaceutical raw materials
Givinostat (ITF2357) structure

Givinostat (ITF2357) 

structure
  • CAS No:

    732302-99-7

  • Formula:

    C24H30ClN3O5

  • Chemical Name:

    Givinostat (ITF2357)

  • Synonyms:

    ITF2357;ITF2357 (Givinostat);N-[4-[(Hydroxyamino)carbonyl]phenyl]carbamic acid [6-[(diethylamino)methyl]-2-naphthalenyl]methyl ester hydrochloride hydrate;(6-((diethylamino)methyl)naphthalen-2-yl)methyl 4-(hydroxycarbamoyl)phenylcarbamate hydrochloride hydrate;Givinostat (hydrochloride monohydrate);Givinostat Hydrochloride Hydrate

  • Categories:

    Biochemical Engineering  >  Inhibitors

Givinostat (ITF2357) Basic Attributes

475.9651

475.187

Characteristics

91.9

Drug Information

Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains. (See all compounds classified as Histone Deacetylase Inhibitors.)

givinostat hydrochloride

Computed Properties

Molecular Weight:476.0
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:475.1873988
Monoisotopic Mass:475.1873988
Topological Polar Surface Area:91.9
Heavy Atom Count:33
Complexity:575
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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