 Home > Encyclopedia > Omecamtiv mecarbil

Omecamtiv mecarbil

Omecamtiv mecarbil structure

CAS No:
873697-71-3
Formula:
C20H24FN5O3
Chemical Name:
Omecamtiv mecarbil
Synonyms:
1-Piperazinecarboxylic acid,4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-,methyl ester;Omecamtiv mecarbil;CK 1827452;Methyl 4-[[2-fluoro-3-[N′-(6-methylpyridin-3-yl)ureido]phenyl]methyl]piperazine-1-carboxylate;921625-14-1
Categories:
Biochemical Engineering > Inhibitors

Request for Quotation

Description

Omecamtiv mecarbil is a cardiac myosin activator.

Omecamtiv mecarbil Basic Attributes

Molecular Weight：

401.4346632

Exact Mass：

401.43

Characteristics

PSA：

86.8

XLogP3：

1.4

Density：

1.3±0.1 g/cm3

Melting Point：

180 °C

Boiling Point：

456.78ºC at 760 mmHg

Flash Point：

230.1±28.7 °C

Refractive Index：

1.639

Omecamtiv mecarbil Use and Manufacturing

CK 1827452 is a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction.

Recommended Suppliers of Omecamtiv mecarbil

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

CK 1827452

CAS No.: 873697-71-3

Content: 99.00%

Inquiry