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CGS 21680A

CGS 21680A structure

CGS 21680A 

structure
  • CAS No:

    124431-80-7

  • Formula:

    C23H30ClN7O6

  • Chemical Name:

    CGS 21680A

  • Synonyms:

    CGS 21680A;CGS 21680 (HCl salt);4-[2-[[6-Amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monohydrochloride;Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]- hydrochloride (1:1)

  • Categories:

    Biochemical Engineering  >  Inhibitors

Description

White to Off-White Solid

CGS 21680A Basic Attributes

535.9806

Characteristics

204-206°C

Refrigerator

CGS 21680A Use and Manufacturing

CGS 21680 is a potent, selective agonist of the adenosine A2A receptor (Ki = 11-46 nM). It is less effective at adenosine A1 and A3 receptors (Kis = 0.5-3.1 and 0.6-1 μM, respectively) and is without effect at adenosine A2B (Ki > 10 μM). CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues.[Cayman Chemical]

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