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BMS707035

BMS707035 structure

CAS No:
729607-74-3
Formula:
C17H19FN4O5S-2
Chemical Name:
BMS707035
Synonyms:
BMS707035;N-[(4-Fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-4-pyrimidinecarboxamide;4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin;2-(1,1-DIOXOTHIAZINAN-2-YL)-N-[(4-FLUOROPHENYL)METHYL]-5-HYDROXY-1-METHYL-6-OXOPYRIMIDINE-4-CARBOXAMIDE
Categories:
Biochemical Engineering > Inhibitors

Description

BMS-707035 is an HIV-1 integrase (IN) inhibitor with an IC50 value of 15 nM. IC50 Value: 15 nMTarget: HIV IntegraseBMS-707035 was scheduled to be evaluated in a Phase II study to assess the antiretroviral activity, safety, pharmacodynamics, and pharmacokinetics in 50 HIV-infected subjects using a 10-day randomized, double-blind, placebo-controlled, ascending multiple-dose study design.

BMS707035 Basic Attributes

Molecular Weight：

410.4199632

Exact Mass：

410.106018

EC Number：

-0

Characteristics

PSA：

128

XLogP3：

Density：

1.5±0.1 g/cm3

Refractive Index：

1.670

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