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CORTISTATIN-14

CORTISTATIN-14 structure

CORTISTATIN-14 

structure
  • CAS No:

    186901-48-4

  • Formula:

    C81H113N19O19S2

  • Chemical Name:

    CORTISTATIN-14

  • Synonyms:

    H-PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS-OH;CST-14;CST-14 (RAT);CORTISTATIN (RAT);CORTISTATIN-14;CORTISTATIN-14 (MOUSE, RAT);CORTISTATIN (16-29);(DES-ALA1,PRO2,SER12)-SOMATOSTATIN-14-LYS

  • Categories:

    Biochemical Engineering  >  Polypeptide

Description

Cortistatin-14, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties[1][2][3][4].

CORTISTATIN-14 Basic Attributes

1721.01

1719.79000

DTXSID00583202

Characteristics

675.86000

3.12890

1.41±0.1 g/cm3(Predicted)

2012.6±65.0 °C(Predicted)

−20°C

Safety Information

NONH for all modes of transport

3

Drug Information

cortistatin|cortistatin 14

Computed Properties

Molecular Weight:1721.0
XLogP3:-2.7
Hydrogen Bond Donor Count:23
Hydrogen Bond Acceptor Count:25
Rotatable Bond Count:30
Exact Mass:1719.79015480
Monoisotopic Mass:1719.79015480
Topological Polar Surface Area:676
Heavy Atom Count:121
Complexity:3400
Defined Atom Stereocenter Count:15
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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