Chonglou Saponin II
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Chonglou Saponin II
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CAS No:
76296-72-5
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Formula:
C44H70O16
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Chemical Name:
Chonglou Saponin II
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Synonyms:
Chonglou Saponin II;Polyphyllin Ⅱ;Polyphyllin II;Polyphyllin II, 98%, from Paris Linnaeus (Paris L.);Polyphyllin II(Chonglou Saponin II);Chonglou saponin Ⅱ;β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-;Polyphyllin ll
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CAS No:
Description
Polyphyllin II is one of the most significant saponins in Rhizoma Paridis and has toxic effects on kinds of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest[1].
White crystalline powder, easily soluble in methanol and water, derived from Paris polyphylla.
Chonglou Saponin II Use and Manufacturing
Polyphylin II is a natural saponin extracted from the plant, Paris polyphylla, and displays antiproliferative activity in vivo.
Computed Properties
Molecular Weight:855.0
XLogP3:1.5
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:8
Exact Mass:854.46638614
Monoisotopic Mass:854.46638614
Topological Polar Surface Area:236
Heavy Atom Count:60
Complexity:1570
Undefined Atom Stereocenter Count:25
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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