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Alisol B acetate

Alisol B acetate structure

CAS No:
26575-95-1
Formula:
C28H44O4
Chemical Name:
Alisol B acetate
Synonyms:
(23S,24R)-24,25-Epoxy-11b,23-dihydroxy-8a,9b,14b-dammar-13(17)-en-3-one 23-acetate;Alisol B acetate;Alisol B 23-acetate,;(8α,9β,14β,23S,24R)-11β-Hydroxy-23-acetoxy-24,25-epoxy-5α-dammara-13(17)-ene-3-one;(8α,9β,14β,23S,24R)-23-Acetoxy-24,25-epoxy-11β-hydroxydammar-13(17)-en-3-one;Acetylalisol B;ALISOL B ACETATE(SH);23-O-Acetylalisol B
Categories:
Biochemical Engineering > Plant Extracts

Description

Alisol B 23-acetate, a natural triterpenoid, produces protective effects against EE-induced cholestasis, due to FXR-mediated gene regulation.IC50 Value:Target: Anti-hepatotoxic natural product. In vitro: Alisol-B 23-acetate has an effect on FXR activation in a dose-dependent manner using luciferase reporter assay in HepG2 cells [3].In vivo: In alisol B 23-acetate-treated mice, the changes in transporters and enzymes, as well as ameliorative liver histology were abrogated by FXR antagonis

Alisol B acetate Basic Attributes

Molecular Weight：

444.65

Exact Mass：

514.365845

HScode：

29153900

Characteristics

Density：

1.1±0.1 g/cm3

Melting Point：

162～163℃

Flash Point：

179.9±23.6 °C

Refractive Index：

1.542

Safety Information

Transport codes：

NONH for all modes of transport

safety instructions：

24/25

Drug Information

MeSH Entry Terms：

23-acetylalisol B

Computed Properties

Molecular Weight:514.7
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:514.36582469
Monoisotopic Mass:514.36582469
Topological Polar Surface Area:76.1
Heavy Atom Count:37
Complexity:1020
Undefined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Lowering blood pressure and lipids

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Bushen Guchi Pills
Ingredients	Rehmannia root, Rehmannia root, Millettia spatholobi, Placenta, Drynaria fortunei, Salvia miltiorrhiza wine, Schisandra chinensis wine, Chinese yam, Curcuma aromatica vinegar, Roasted Astragalus, Achyranthes bidentata, Chrysanthemum indicum, Poria, Fructus Lycii, Peony bark, Alisma orientalis salt, Cinnamon bark. Excipients: Salt, film coating agent.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	Each 30 pills weigh 1 gram
Manufacturer	Chengdu Jiuzhitang Jinding Pharmaceutical Co., Ltd.

Shanju Antihypertensive Capsules
Ingredients	Hawthorn, selfheal, chrysanthemum, thistle, salt alisma, and stir-fried cassia seed.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	0.5g per capsule
Manufacturer	Nanjing Tongrentang Pharmaceutical Co., Ltd.

Bear Bile Pills (Longze Bear Bile Capsules)
Ingredients	Gentian, salt alisma, rehmannia root, angelica root, gardenia, chrysanthemum, salt plantain seed, cassia seed, bupleurum root, siler, scutellaria root, equisetum, coptis root, menthol, rhubarb, borneol, bear bile powder. The auxiliary material is starch.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	12 tablets/plate x 2 plates/box, each tablet contains 0.25g.
Manufacturer	Yunnan Dali Ruihe Pharmaceutical Co., Ltd.

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Alisol B acetate

CAS No.: 26575-95-1

Content: 99.00%

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Alisol B 23-monoacetate 99% see COA kanbei

CAS No.: 26575-95-1

Grade: Industrial Grade

Content: 99%

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Guide of Alisol B acetate

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Computed Properties
Drug Function and Efficacy
Related Drugs
Recommended Suppliers
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Alisol B acetate

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