BPP 9A
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BPP 9A
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CAS No:
35115-60-7
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Formula:
C53H76N14O12
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Chemical Name:
BPP 9A
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Synonyms:
teprotide;PGLU-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO;PYR-WPRPQIPP;PYROGLU-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO;PYR-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO;PYR-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO-OH;SQ 20881;GLP-TRP-PRO-ARG-PRO-GLN-ILE-PRO-PRO
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CAS No:
Description
Teprotide is a peptide.|A synthetic nonapeptide (Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) which is identical to the peptide from the venom of the snake, Bothrops jararaca. It inhibits kininase II and ANGIOTENSIN I and has been proposed as an antihypertensive agent.
Drug Information
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. (See all compounds classified as Angiotensin-Converting Enzyme Inhibitors.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)
BPP-9a
Computed Properties
Molecular Weight:1101.3
XLogP3:-0.9
Hydrogen Bond Donor Count:10
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:24
Exact Mass:1100.57671391
Monoisotopic Mass:1100.57671391
Topological Polar Surface Area:387
Heavy Atom Count:79
Complexity:2330
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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