Albiflorin
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Albiflorin
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CAS No:
39011-90-0
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Formula:
C23H28O11
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Chemical Name:
Albiflorin
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Synonyms:
7-Oxatricyclo[4.3.0.03,9]nonan-8-one,9-[(benzoyloxy)methyl]-1-(β-D-glucopyranosyloxy)-4-hydroxy-6-methyl-,(1R,3R,4R,6S,9S)-;(1R,3R,4R,6S,9S)-9-[(Benzoyloxy)methyl]-1-(β-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclo[4.3.0.03,9]nonan-8-one;Albiflorin
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CAS No:
Description
Albiflorin is a major constituent contained in peony root; possesses therapeutic potential for neurodegenerative diseases.IC50 value:Target: in vitro: Albiflorin significantly ameliorated Glu-induced reduction of cell viability, nuclear and mitochondrial apoptotic alteration, reactive oxygen species accumulation, and B-cell lymphoma 2 (Bcl-2)/Bax ratio. Albiflorin also enhanced phosphorylation of AKT and its downstream element glycogen synthase kinase-3β, and this effect was abrogated by
Characteristics
172.21000
-1.51490
White powder
1.6±0.1 g/cm3
722.1ºC at 760 mmHg
248.9±26.4 °C
1.662
-20°C
Computed Properties
Molecular Weight:480.5
XLogP3:-1
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:7
Exact Mass:480.16316171
Monoisotopic Mass:480.16316171
Topological Polar Surface Area:172
Heavy Atom Count:34
Complexity:830
Defined Atom Stereocenter Count:5
Undefined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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