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1-(Triphenylmethyl)-L-histidine

1-(Triphenylmethyl)-L-histidine structure

CAS No:
35146-32-8
Formula:
C25H23N3O2
Chemical Name:
1-(Triphenylmethyl)-L-histidine
Synonyms:
L-Histidine,1-(triphenylmethyl)-;1-(Triphenylmethyl)-L-histidine;(S)-2-Amino-3-(1-trityl-1H-imidazol-4-yl)propanoic acid
Categories:
Biochemical Engineering > Amino Acids and Derivatives

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Description

White powder

1-(Triphenylmethyl)-L-histidine Basic Attributes

Molecular Weight：

397.47

Exact Mass：

397.47

EC Number：

1308068-626-2

DSSTox ID：

DTXSID90428597

HScode：

2933290090

Characteristics

PSA：

81.1

XLogP3：

1.5

Appearance：

Solid

Density：

1.2±0.1 g/cm3

Melting Point：

221 °C

Boiling Point：

584.8°C at 760 mmHg

Flash Point：

307.5±30.1 °C

Refractive Index：

1.632

Storage Conditions：

−20°C

Safety Information

wgk germany：

1-(Triphenylmethyl)-L-histidine Use and Manufacturing

Fmoc-His(Trt)-OH 100 g 0.161 mol 1 Eq Piperidine 140 g 1.614 mol 10 EqTHF 2000 ml lOOg Fmoc-His(Trt)-OH are dissolved in 2000 mL THF and treated with 140 g piperidine for 2 h under stirring with a mechanical stirrer blade. TLC indicated complete FMOC removal after that period.Water (approximately 4 L) was added and stirred for another 30 minutes. The precipitate was filtered with suction. The clear filtrate was concentrated to remove all TFfF. The pH was adjusted to 2.5 with dilute HCl and the mixture stirred overnight. Filtration yielded 53 g colorless crystals (83 percent), which were dried in the air overnight.

Computed Properties

Molecular Weight:397.5
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:397.17902698
Monoisotopic Mass:397.17902698
Topological Polar Surface Area:81.1
Heavy Atom Count:30
Complexity:505
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 1-(Triphenylmethyl)-L-histidine

Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

His(TRT)-OH 99% see COA kanbei

CAS No.: 35146-32-8

Grade: Industrial Grade

Content: 99%

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Hangzhou Chungyo Chemicals Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals

H-His(trt)-OH

CAS No.: 35146-32-8

Grade: pharmaceutical grade

Content: 98%

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Guide of 1-(Triphenylmethyl)-L-histidine

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

1-(Triphenylmethyl)-L-histidine

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