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Peimine

Peimine structure

CAS No:
23496-41-5
Formula:
C27H45NO3
Chemical Name:
Peimine
Synonyms:
Cevane-3,6,20-triol,(3β,5α,6α)-;5α-Cevane-3β,6α,20-triol;Verticine;(3β,5α,6α)-Cevane-3,6,20-triol;Dihydroisoimperialine;Peimine;1360-30-1
Categories:
Biochemical Engineering > Chinese Herbs

Description

Peimine(Dihydroisoimperialine; Verticine) is a natural compound with good anti-inflammatory effects in vivo.IC50 value:Target:Peimine (0-25 mg/L) significantly inhibited tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-1β, and increased IL-10 production. Furthermore, peimine significantly inhibited the phosphorylation of p38, ERK and c-jun N-terminal kinase (JNK) as well as decreased p65 and IκB.

Verticine is an alkaloid.

Peimine Basic Attributes

Molecular Weight：

431.65

Exact Mass：

431.65

UNII：

34QDF8UFSY

HScode：

29420000

Characteristics

PSA：

63.9

XLogP3：

4.1

Appearance：

White powder

Density：

1.2±0.1 g/cm3

Melting Point：

223 °C

Boiling Point：

568.4°C at 760 mmHg

Flash Point：

275.3±28.8 °C

Refractive Index：

1.591

Vapor Pressure：

2.74E-15mmHg at 25°C

Specific rotation：

D16 -19.4° (ethanol); D17 -20° (CHCl3)

Safety Information

Transport codes：

NONH for all modes of transport

safety instructions：

24/25

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P501

Hazard Statements：

H302

Drug Information

MeSH Entry Terms：

peimine

Computed Properties

Molecular Weight:431.7
XLogP3:4.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Exact Mass:431.33994430
Monoisotopic Mass:431.33994430
Topological Polar Surface Area:63.9
Heavy Atom Count:31
Complexity:715
Defined Atom Stereocenter Count:13
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Regulates Na+/K+-ATPase activity to exert cough-suppressing and expectorant effects

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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Manufacturer	Prima Fleur Botanicals, Inc.

THEPURI DEEP PURE HAND SANITIZER- ethyl alcohol_gel
Manufacturer	E.CIS COSMETIC.Co.,Ltd

Recommended Suppliers of Peimine

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

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Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Peimine

CAS No.: 23496-41-5

Content: 99.00%

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Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

Peimine 99% white powder kanbei

CAS No.: 23496-41-5

Grade: Industrial Grade

Content: 99%

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Guide of Peimine

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Computed Properties
Drug Function and Efficacy
Related Drugs
Recommended Suppliers
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