POLY(D,L-LACTIDE-CO-GLYCOLIDE)
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POLY(D,L-LACTIDE-CO-GLYCOLIDE)
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CAS No:
26780-50-7
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Formula:
(C6H8O4.C4H4O4)x
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Chemical Name:
POLY(D,L-LACTIDE-CO-GLYCOLIDE)
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Synonyms:
RESOMER?RG 503 H;POLY(DL-LACTIDE-CO-GLYCOLIDE) (65:35);POLY(DL-LACTIDE-CO-GLYCOLIDE) 65:35*M.W. 40,000-75,;POLY(DL-LACTIDE-CO-GLYCOLIDE) (75:25);DL-LACTIDE/GLYCOLIDE COPOLYMER;LACTEL BP-0100;LACTEL BP-0200;LACTEL BP-0300
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CAS No:
Description
intrinsic viscosity 0.15-0.25
A polyester used for absorbable sutures and surgical mesh, especially in ophthalmic surgery. 2-Hydroxy-propanoic acid polymer with polymerized hydroxyacetic acid, which forms 3,6-dimethyl-1,4-dioxane-dione polymer with 1,4-dioxane-2,5-dione copolymer of molecular weight about 80,000 daltons.
Ester terminated Poly(D,L-lactide) (PDLLA, RESOMER) is a copolymer of L and D-lactic acid and (or L and D lactide). The structure is highly irregular and amorphous. RESOMERpolymers are bioresorbable aliphatic polyesters comprised of a range of different ratios of lactide and glycolide monomers, PLA stereochemistries, and end-group functionalization.
Characteristics
105
-1.00500
White to tan Crystalline Powder or Granules
1.34 g/cm³ (membranes)
165.09 °C
113℃
ethyl acetate, chloroform, acetone and THF: soluble
−20°C
2-8°C
Safety Information
NONH for all modes of transport
3
P261, P272, P280, P302+P352, P321, P333+P313, P363, P501
H317
POLY(D,L-LACTIDE-CO-GLYCOLIDE) Use and Manufacturing
Controlled release
Poly(D,L-lactide), Resomer R203s is a copolymer of 1,4-Dioxane-2,5-dione (D485883) and DL-Lactide (L113518). Because the copolymer is biocompatible and biodegradable it is used for controlled release of drugs and therapeutic agents.
Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics.
Computed Properties
Molecular Weight:260.20
Hydrogen Bond Acceptor Count:8
Exact Mass:260.05321734
Monoisotopic Mass:260.05321734
Topological Polar Surface Area:105
Heavy Atom Count:18
Complexity:267
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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