(±)-Poly(lactic acid)
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(±)-Poly(lactic acid)
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CAS No:
26100-51-6
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Formula:
(C3H6O3)x
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Chemical Name:
(±)-Poly(lactic acid)
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Synonyms:
Propanoic acid,2-hydroxy-,homopolymer;Lactic acid,polymers;Lactic acid,polyesters;Poly(lactic acid);Lactic acid polymer;Lactic acid homopolymer;(±)-Lactic acid homopolymer;(±)-2-Hydroxypropanoic acid homopolymer;Poly(DL-lactic acid);Poly(dl-lactate);(±)-Poly(lactic acid);DL-Polylactic acid;Poly(dl-lactic acid);DL-Lactic acid polymer;DL-Lactic acid homopolymer;Polylactic acid;NeoOrtho;D,L-polylactic acid;2-Hydroxypropanoic acid homopolymer;Polylactate;Lactates,polylactates;Polylactates;PLA;31587-11-8;947236-64-8;1104201-86-6;1148011-07-7;1384255-85-9
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CAS No:
Characteristics
57.5
-0.6
black
1.21 g/cm3
173 °C
122 deg C at 15 mm Hg
110°C c.c.
1.451
Solubility in water: miscible
2-8°C
0.0813 mm Hg at 25 deg C
Safety Information
NONH for all modes of transport
3
36
22-24/25-26
OD2800000
Xi
Separated from strong bases.
Stable under recommended storage conditions.
P264, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P362
H315
(±)-Poly(lactic acid) Use and Manufacturing
polylactic acid (PLA) is a lactic acid polymer that can be used as a filler. Polylactic acid(PLA) was introduced in 1966 for degradable surgical implants. Hydrolysis yields lactic acid, a normal intermediate of carbohydrate metabolism. Polyglycolic acid sutures have a predictable degradation rate which coincides with the healing sequence of natural tissues.
Polylactic acid, also known as polylactide, is prepared from the cyclic diester of lactic acid (lactide) by ring-opening addition polymerization. Pure DL-lactide displays greater bioresorbability, whereas pure poly-Llactide is more hydrolytically resistant.
The actual time required for poly-L-lactide implants to be completely absorbed is relatively long, and depends on polymer purity, processing conditions, implant site, and physical dimensions of the implant.
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