Cycloastragenol
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Cycloastragenol
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CAS No:
78574-94-4
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Formula:
C30H50O5
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Chemical Name:
Cycloastragenol
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Synonyms:
9,19-Cyclolanostane-3,6,16,25-tetrol,20,24-epoxy-,(3β,6α,16β,20R,24S)-;(3β,6α,16β,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;Cyclosiversigenin;Astramembrangenin;Cycloastragenol;Cyclosieversigenin;Cyloastragenol;89396-45-2
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CAS No:
Description
Astramembrangenin (Cycloastragenol) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus (Fisch.) Bunge[1].Astramembrangenin is orally safe and has broad Extensive pharmacological effects, including telomerase activation, telomere elongation, anti-inflammatory and anti-oxidative properties[2].Astramembrangenin has antiaging properties, CAG stimulates telomerase activity in human neonatal keratinocytes and rat neuronal cells,
Cycloastragenol is a sapogenin that is the aglycone derivative of astragaloside IV, a major saponin extracted from the root of Astragalus membranaceus. It has a role as a metabolite. It is a sapogenin, a pentacyclic triterpenoid, a tetrol and a member of oxolanes. It derives from a hydride of a 5alpha-gonane.
Characteristics
90.2
4.4
1.2±0.1 g/cm3
239-241 °C @ Solvent: Methanol
617.2±55.0°C at 760 mmHg
327.1±31.5 °C
1.582
Computed Properties
Molecular Weight:490.7
XLogP3:4.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:490.36582469
Monoisotopic Mass:490.36582469
Topological Polar Surface Area:90.2
Heavy Atom Count:35
Complexity:916
Defined Atom Stereocenter Count:12
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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