 Home > Encyclopedia > Jaceosidin

Jaceosidin

Jaceosidin structure

CAS No:
18085-97-7
Formula:
C17H14O7
Chemical Name:
Jaceosidin
Synonyms:
4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-;Flavone,4′,5,7-trihydroxy-3′,6-dimethoxy-;5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;Jaceosidin;3′,6-Dimethoxy-4′,5,7-trihydroxyflavone;4′,5,7-Trihydroxy-3′,6-dimethoxyflavone;4′-Demethyleupatilin;5,7,4′-Trihydroxy-6,3′-dimethoxyflavone;6-Methoxyluteolin 3′-methyl ether;6-Hydroxyluteolin 6,3′-dimethyl ether;Jaseocidin
Categories:
Natural Products > Flavonoids

Description

Jaceosidin is a flavonoid isolated from Artemisia vestita, induces apoptosis in cancer cells, activates Bax and down-regulates Mcl-1 and c-FLIP expression[1]. Jaceosidin exhibits anti-cancer[2], anti-inflammatory activities, decreases leves of inflammatory markers, and suppresses COX-2 expression and NF-κB activation[3].

Jaceosidin is a trihydroxyflavone that is flavone with hydroxy groups at positions 5, 7 and 4' and methoxy groups at positions 3' and 6. Isolated from Salvia tomentosa and Artemisia asiatica, it exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties. It has a role as a metabolite, an anti-inflammatory agent, an apoptosis inducer, an anti-allergic agent and an antineoplastic agent. It is a trihydroxyflavone and a dimethoxyflavone.

Jaceosidin Basic Attributes

Molecular Weight：

330.29

Exact Mass：

330.29

DSSTox ID：

DTXSID00171022

HScode：

2914509090

Characteristics

PSA：

105

XLogP3：

1.7

Density：

1.5±0.1 g/cm3

Melting Point：

259-260 °C

Boiling Point：

619°C at 760 mmHg

Flash Point：

232.0±25.0 °C

Refractive Index：

1.671

Vapor Pressure：

6.48E-16mmHg at 25°C

Drug Information

Metabolism/Metabolites：

Jaceosidine is a known human metabolite of eupatilin.

MeSH Entry Terms：

jaceosidin

Jaceosidin Use and Manufacturing

Use Classification：

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:330.29
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:330.07395278
Monoisotopic Mass:330.07395278
Topological Polar Surface Area:105
Heavy Atom Count:24
Complexity:505
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Jaceosidin

Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

Jaceosidin powder herbal extract 18085-97-7

CAS No.: 18085-97-7

Grade: Chemical Grade

Content: 99%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

4,5,7-Trihydroxy-3,6-dimethoxyflavone

CAS No.: 18085-97-7

Content: 99.00%

Inquiry

Learn More Other Chemicals

Heliannone A

193411-10-8
Linustatin

72229-40-4
1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-3-[(2-O-β-D-glucopyranosyl-α-D-glucopyranosyl)oxy]-5,7-dihydroxy-, chloride (1:1)

38820-68-7
(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1Z)-1-propen-1-ylestra-4,9-dien-3-one Formula

124478-60-0
3',4',5',3,5,6,7-Heptamethoxyflavone Formula

17245-30-6
(-)-8-Prenylnaringenin Formula

53846-50-7
Cirsimaritin Structure

6601-62-3
5,7,4'-trihydroxy-8-methoxyflavone Structure

57096-02-3
What is Desmethylicaritin

28610-31-3
What is Ombuoside

20188-85-6

Hot Searches: potassium ocide; medetomidine for sale; 2cb sale; ordering retatrutide; eriochrome black t msds; dimethylmercury

Guide of Jaceosidin

Description
Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

Jaceosidin

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.