(Z)-3,5,4′-Trimethoxystilbene
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(Z)-3,5,4′-Trimethoxystilbene
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CAS No:
94608-23-8
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Formula:
C17H18O3
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Chemical Name:
(Z)-3,5,4′-Trimethoxystilbene
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Synonyms:
Benzene,1,3-dimethoxy-5-[(1Z)-2-(4-methoxyphenyl)ethenyl]-;Benzene,1,3-dimethoxy-5-[2-(4-methoxyphenyl)ethenyl]-,(Z)-;1,3-Dimethoxy-5-[(1Z)-2-(4-methoxyphenyl)ethenyl]benzene;3,4′,5-Trimethoxy-cis-stilbene;(Z)-3,5,4′-Trimethoxystilbene;(Z)-1-(4-Methoxyphenyl)-2-(3,5-dimethoxyphenyl)ethene
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CAS No:
(Z)-3,5,4′-Trimethoxystilbene Use and Manufacturing
Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities.In addition, resveratrol activates sirtuins and, in yeast, extends lifespan. cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells.It inhibits tubulin polymerization in a dose-dependent manner (IC50 =4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine.trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.
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