Elastase
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Elastase
structure -
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CAS No:
39445-21-1
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Formula:
NULL
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Chemical Name:
Elastase
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Synonyms:
EC 3.4.21.36;EC 3.4.21.37;ELASTASE, LEUKOCYTE;ELASTASE, NEUTROPHIL, HUMAN;ELASTASE, HUMAN NEUTROPHIL;ELASTASE, HUMAN NEUTROPHILS;LEUKOCYTE ELASTASE, HUMAN NEUTROPHILS;LYSOSOMAL ELASTASE
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CAS No:
Safety Information
NONH for all modes of transport
3
36/37/38-42
23-24-26-36/37-22
TS5052000
B,Xn
P261-P280-P284-P304 + P340 + P312-P305 + P351 + P338-P337 + P313-P342 + P311
H315-H319-H334-H335
Elastase Use and Manufacturing
A serine protease that can hydrolyze amino compounds and esters. The special feature of elastase is that it can act on elastin. The optimal pH value for enzyme action is 8.5. Soybean trypsin inhibitor and kallikrein inhibitor can inhibit its proteolytic activity, but cannot inhibit its elastin hydrolytic activity.
Drug Function and Efficacy
This product is an endopeptidase that can hydrolyze elastin, collagen and glycoprotein, enhance the activity of lipoprotein esterase, prevent the synthesis of cholesterol in the body and promote its conversion into bile acid, reduce plasma cholesterol, LDL, VLDL and triglycerides, increase HDL, prevent lipid deposition on the arterial wall, decompose old elastin and promote the synthesis of new elastin, maintain vascular elasticity, inhibit the hypertrophy of glomerular basement membrane, and reduce the excretion of trace protein in the kidney.
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