Fenoprofen calcium salt hydrate

The main ingredient of this product is fenoprofen calcium

1 When used with alcohol or other non-steroidal anti-inflammatory drugs, gastrointestinal side effects increase and there is a risk of ulcers. Long-term use with acetaminophen may increase toxic side effects on the kidneys. 2 When used with aspirin or other salicylic acid drugs, the efficacy is not enhanced, but the incidence of gastrointestinal adverse reactions and bleeding tendency increases. 3 When used with anticoagulants such as heparin and dicoumarol and platelet aggregation inhibitors, there is an increased risk of bleeding. 4 When used with furosemide, the latter's sodium excretion and antihypertensive effects are weakened. 5 When used with verapamil and nifedipine, the blood concentration of this product increases. 6 This product can increase the blood concentration of digoxin.

The main ingredient of this product is fenoprofen calcium

1 When used with alcohol or other non-steroidal anti-inflammatory drugs, gastrointestinal side effects increase and there is a risk of ulcers. Long-term use with acetaminophen may increase toxic side effects on the kidneys. 2 When used with aspirin or other salicylic acid drugs, the efficacy is not enhanced, but the incidence of gastrointestinal adverse reactions and bleeding tendency increases. 3 When used with anticoagulants such as heparin and dicoumarol and platelet aggregation inhibitors, there is an increased risk of bleeding. 4 When used with furosemide, the latter's sodium excretion and antihypertensive effects are weakened. 5 When used with verapamil and nifedipine, the blood concentration of this product increases. 6 This product can increase the blood concentration of digoxin.

The main ingredient of this product is: Fenoprofen calcium. Its chemical name is: ?-Methyl-3-phenoxy-phenylacetic acid calcium dihydrate. Molecular formula: C30H26CaO62H2O Molecular weight: 558.64

(1) When used with alcohol or other non-steroidal anti-inflammatory drugs, gastrointestinal side effects may increase, and there is a risk of ulcers. Long-term use with acetaminophen may increase kidney toxicity. (2) When used with aspirin or other salicylic acid drugs, the bioavailability of this product may be reduced, the efficacy will not be enhanced, and the incidence of gastrointestinal adverse reactions and bleeding tendency will increase. (3) When used with anticoagulants such as heparin and dicoumarol and platelet aggregation inhibitors, there is an increased risk of bleeding. (4) When used with furosemide, the latter's sodium excretion and antihypertensive effects are weakened. (5) When used with verapamil and nifedipine, the blood concentration of this product increases. (6) This product can increase the blood concentration of digoxin. When used at the same time, the dosage of digoxin should be adjusted. (7) This product can enhance the effect of antidiabetic drugs (including oral hypoglycemic drugs). (8) When used with antihypertensive drugs, this product may affect the antihypertensive effect of the latter. (9) Probenecid can reduce the excretion of this product, increase its blood concentration, and thus increase its toxicity. Therefore, it is advisable to reduce the dosage of this product when used simultaneously. ⑽ This product can reduce the excretion of methotrexate, increase its blood concentration, and even reach toxic levels. Therefore, this product should not be used simultaneously with medium or large doses of methotrexate. ⑾ This product does not affect absorption when taken together with antacids containing aluminum and magnesium. When used together with antacids for a long time, the blood concentration may be significantly reduced. When used together with phenobarbital, the excretion half-life of this product is shortened, which may be related to the increase in liver enzyme activity that accelerates the metabolism of this product. At this time, the dosage of this product needs to be adjusted.