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Home > Encyclopedia > Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3)

Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3)

pharmaceutical raw materials
Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3) structure

Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3) 

structure
  • CAS No:

    41354-29-4

  • Formula:

    C21H21N.ClH.3/2H2O

  • Chemical Name:

    Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3)

  • Synonyms:

    Piperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-,hydrochloride,hydrate (2:2:3);Piperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-,hydrochloride,hydrate (2:3);Cyproheptadine hydrochloride sesquihydrate

  • Categories:

    Active Pharmaceutical Ingredients  >  Antiallergic Drugs

Description

Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine2.

Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3) Basic Attributes

323.86

213-535-1

29333990

Characteristics

12.47000

5.37350

white to slightly yellow

165 °C (dec.)(lit.)

440.1°C at 760 mmHg

194.5ºC

ethanol: soluble

LD50 orally in mice: 74.2 mg/kg (Loux)

Safety Information

6.1

UN 2811 6.1/PG 3

3

22-36/37/38

26-36

TM7050000

Xn

P261-P305 + P351 + P338

H302-H315-H319-H335

Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3) Use and Manufacturing

Cyproheptadine is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. Cyproheptadine is a 5-HT2/5-HT1C serotonin receptor antagonist; H1 histamine receptor antagonist; antipruritic.

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