Mitiglinide calcium dihydrate
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Mitiglinide calcium dihydrate
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CAS No:
207844-01-7
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Formula:
C38H52CaN2O8
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Chemical Name:
Mitiglinide calcium dihydrate
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Synonyms:
(aS,3aR,7aS)-Octahydro-gamma-oxo-alpha-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt dihydrate;(S)-2-Benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric acid calcium salt dihydrate;Mitiglinide calcium;3006 MITIGLINIDE CALCIUM HYDRATE;2H-ISOINDOLE-2-BUTANOICACID,OCTAHYDRO-G-OXO-A-(PHENYLMETHYL)-,CALCIUMSALT,DIHYDRATE;Mitiglinide CalciuM dihydrate;(S)-2-Benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric Acid Calcium Salt Hydrate;KAD-1229 Calcium Hydrate
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Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System
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CAS No:
Description
Mitiglinide calcium hydrate is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. IC50 value:Target: KATP channel
Mitiglinide calcium hydrate (KAD-1229) is an insulinotropic agent. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
White Solid
Characteristics
111.68000
5.53020
white solid
179-185°C
-20°C Freezer
Inert atmosphere,Room Temperature
Mitiglinide calcium dihydrate Use and Manufacturing
KAD-1229 binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Antidiabetic
Drug Function and Efficacy
The pharmacological effects extracted from the above information are not clearly described.
Registered Holders
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Shandong Boyuan Pharmaceutical Co., Ltd.
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China
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Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
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China
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Zhejiang Guobang Pharmaceutical Co., Ltd.
Active![China]()
China
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