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3-Amino-2-bromo-5-fluoropyridine

3-Amino-2-bromo-5-fluoropyridine structure

CAS No:
884495-03-8
Formula:
C5H4BrFN2
Chemical Name:
3-Amino-2-bromo-5-fluoropyridine
Synonyms:
3-AMINO-2-BROMO-5-FLUOROPYRIDINE;2-bromo-5-fluoropyridin-3-amine;2-Bromo-5-fluoro-3-pyridinamine;2-broMo-5-fluoro-3-aMinopyridine
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

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3-Amino-2-bromo-5-fluoropyridine Basic Attributes

Molecular Weight：

191

Exact Mass：

189.954178

HScode：

2933399090

Characteristics

PSA：

38.9

XLogP3：

1.3

Density：

1.8±0.1 g/cm3

Melting Point：

114-116 °C

Boiling Point：

273.6°C at 760 mmHg

Flash Point：

119.3±25.9 °C

Refractive Index：

1.605

Safety Information

wgk germany：

hazard class code：

22-41

safety instructions：

26-39

Marks：

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H302

3-Amino-2-bromo-5-fluoropyridine Use and Manufacturing

step 1 : A suspension of 2-bromo-5-fluoro-3-nitropyridine (4.42 g, 20 mmol) and SnC (22.56 g, 100 mmol) in EtOH (40 mL) and concentrated HC1 (40 mL) was heated at 60 °C for 1 h. The reaction mixture was concentrated under reduced pressure. To the residue was added EtOAc (100 mL) and sat'd aq. NaHC0To a stirred solution of 10.0 g (52.36 mmol)

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3-Amino-2-bromo-5-fluoropyridine

CAS No.: 884495-03-8

Content: 99.00%

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Guide of 3-Amino-2-bromo-5-fluoropyridine

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
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3-Amino-2-bromo-5-fluoropyridine

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