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Home > Encyclopedia > 3,5-Dibromo-2-methylpyridine

3,5-Dibromo-2-methylpyridine

3,5-Dibromo-2-methylpyridine structure

3,5-Dibromo-2-methylpyridine 

structure

3,5-Dibromo-2-methylpyridine Basic Attributes

250.9186

250.92

DTXSID60347281

2933399090

Characteristics

12.9

2.6

1.9±0.1 g/cm3

227.9°C at 760 mmHg

91.6±25.9 °C

1.594

Safety Information

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

3,5-Dibromo-2-methylpyridine Use and Manufacturing

To a solution of 3, 5-dibromo-6-methyl-pyridin-2-ylamine (2.0 g, 7.5 mmol) in THF (75 mL) was added t-butylnitrite (1.5 mL, 12.6 mmol) and the reaction was heated to reflux for 2 hours. The reaction was concentrated in vacuo and purified by flash chromatography (SiO[0512] Step 1: Synthesis of 5-bromo-2'-(tert-butyl)-6-methyl-3, 4'-bipyridine. In a 48 mL glass seal tube was combined A mixture of tributyl-[6-(difluoromethyl)imidazo[1, 2-b]pyridazin-3-yl]stannane (104 mg, 0.227 mmol), A mixture of tributyl-[6-(difluoromethyl)imidazo[1, 2-b]pyridazin-3-yl]stannane (104 mg, 0.227 mmol), Step 1: Preparation of (/f)-2-(5-bromo-6-methyl-pyridin-3-ylamino)-2-phenyl-ethanol Chiral Under an Ar atmosphere, a mixture of To a solution of

Computed Properties

Molecular Weight:250.92
XLogP3:2.6
Hydrogen Bond Acceptor Count:1
Exact Mass:250.87682
Monoisotopic Mass:248.87887
Topological Polar Surface Area:12.9
Heavy Atom Count:9
Complexity:97.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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