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AS703026

AS703026 structure

CAS No:
1236699-92-5
Formula:
C15H15FIN3O3
Chemical Name:
AS703026
Synonyms:
AS703026;N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide;(S)-N-(2,3-dihydroxypropyl)-3-(2-fluoro-4-iodophenylaMino)isonicotinaMide;4-PyridinecarboxaMide, N-[(2S)-2,3-dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)aMino]-;MSC1936369B;PiMasertib (AS-703026);AS703026/MSC1936369B;PiMasertib
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

Pimasertib (AS703026) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2, used for cancer treatment.

AS703026 Basic Attributes

Molecular Weight：

431.2007732

Exact Mass：

431.014191

Characteristics

PSA：

94.5

XLogP3：

1.7

Density：

1.769

Flash Point：

330.7±31.5 °C

Refractive Index：

1.684

AS703026 Use and Manufacturing

AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor, in human multiple myeloma (MM). AS703026 induces pleiotropic anti-myeloma activity in vitro and in vivo. MEK inhibitors are useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation.

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AS703026

CAS No.: 1236699-92-5

Content: 99%

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