Fluorescamine
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Fluorescamine
structure -
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CAS No:
38183-12-9
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Formula:
C17H10O4
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Chemical Name:
Fluorescamine
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Synonyms:
Spiro[furan-2(3H),1′(3′H)-isobenzofuran]-3,3′-dione,4-phenyl-;4-Phenylspiro[furan-2(3H),1′(3′H)-isobenzofuran]-3,3′-dione;4-Phenylspiro[furan-2(3H),1′-phthalan]-3,3′-dione;Fluorescamine;Ro 20-7234;Fluram
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CAS No:
Description
Fluorescamine( Ro 20-7234) is a spiro compound that is not fluorescent itself, but reacts with primary amines to form highly fluorescent products. It hence has been used as a reagent for the detection of amines and peptides.
A nonfluorescent reagent for the detection of primary amines, peptides and proteins. The reaction products are highly fluorescent.
Characteristics
52.6
2.9
off-white to yellow powder
1.4±0.1 g/cm3
154.5 °C
550.3°C at 760 mmHg
-17 °C
1.687
soluble in acetone, ethanol, chloroform, dimethylsulfoxide and acetonitrile. Slightly soluble in water.acetonitrile: soluble
2-8°C
Safety Information
UN 1090 3/PG 2
3
11-36/38-66-67-36-36/37/38
22-24/25-36/37-33-29-26-16-9-37/39
F,Xi
Stable. Incompatible with strong oxidizing agents.
Drug Information
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)
Fluorescamine
Computed Properties
Molecular Weight:278.26
XLogP3:2.9
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:278.05790880
Monoisotopic Mass:278.05790880
Topological Polar Surface Area:52.6
Heavy Atom Count:21
Complexity:503
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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