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Pyrazidole

Pyrazidole structure

Pyrazidole 

structure
  • CAS No:

    16154-78-2

  • Formula:

    C15H18N2.ClH

  • Chemical Name:

    Pyrazidole

  • Synonyms:

    1H-Pyrazino[3,2,1-jk]carbazole,2,3,3a,4,5,6-hexahydro-8-methyl-,hydrochloride (1:1);1H-Pyrazino[3,2,1-jk]carbazole,2,3,3a,4,5,6-hexahydro-8-methyl-,monohydrochloride;Pyrazidole;Pyrazidol;Pirlindole hydrochloride;Pirazidol;2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole monohydrochloride

Pyrazidole Basic Attributes

262.77776

262.124

240-307-9

DTXSID8048230

2933990090

Characteristics

17

2.8

1.29g/cm3

260-264 °C

369

209.4ºC

>39.4 [ug/mL]

2.39E-07mmHg at 25°C

Drug Information

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)|Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)|A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)

1,10-trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-a)indole

Computed Properties

Molecular Weight:262.78
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Exact Mass:262.1236763
Monoisotopic Mass:262.1236763
Topological Polar Surface Area:17
Heavy Atom Count:18
Complexity:303
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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