Eritadenine
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Eritadenine
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CAS No:
23918-98-1
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Formula:
C9H11N5O4
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Chemical Name:
Eritadenine
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Synonyms:
9H-Purine-9-butanoic acid,6-amino-α,β-dihydroxy-,(αR,βR)-;9H-Purine-9-butanoic acid,6-amino-α,β-dihydroxy-,[R-(R*,R*)]-;Erythronic acid,4-(6-amino-9H-purin-9-yl)-4-deoxy-,D-;(αR,βR)-6-Amino-α,β-dihydroxy-9H-purine-9-butanoic acid;Lentinacin;Lentysine;Eritadenine;4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic acid;4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic acid;4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric acid;D-Eritadenine;25486-40-2
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CAS No:
Characteristics
147
-1.8
1.92g/cm3
279 °C
721℃
390℃
1.823
Refrigerator
7.75E-22mmHg at 25°C
D +51.4° (c = 1.6 in 0.1N NaOH)
Drug Information
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)
6-amino-alpha,beta-dihydroxy-9H-purine-9-butanoic acid
Eritadenine Use and Manufacturing
Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.
Computed Properties
Molecular Weight:253.22
XLogP3:-1.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:253.08110385
Monoisotopic Mass:253.08110385
Topological Polar Surface Area:147
Heavy Atom Count:18
Complexity:317
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes