(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
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(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
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CAS No:
103439-17-4
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Formula:
2C6H12NO5P
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Chemical Name:
(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
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Synonyms:
Z-CYCLOPENTYL-AP4;103439-17-4;cis-(+/-)-1-Amino-3-phosphonocyclopentane carboxylic acid;AKOS024457506;(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
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CAS No:
(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO Use and Manufacturing
Group III mGlu receptor agonist that exhibits higher potency at mGlu 4 than mGlu 8 (EC 50 values are 49 and 124 μ M respectively) with no activity at mGlu 7 . Selectively inhibits synaptic activity in the lateral perforant pathway (IC 50 values are 130 and 1859 μ M in the lateral and medial perforant pathways respectively). Conformationally restrained analog of L-AP4 (Cat No. 0103 ).
Computed Properties
Molecular Weight:418.27
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:4
Exact Mass:418.09061896
Monoisotopic Mass:418.09061896
Topological Polar Surface Area:242
Heavy Atom Count:26
Complexity:274
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
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