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1,2-Benzisoxazol-6-amine

1,2-Benzisoxazol-6-amine structure

CAS No:
828300-70-5
Formula:
C7H6N2O
Chemical Name:
1,2-Benzisoxazol-6-amine
Synonyms:
1,2-Benzisoxazol-6-amine;1,2-Benzoxazol-6-amine
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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1,2-Benzisoxazol-6-amine Basic Attributes

Molecular Weight：

134.14

Exact Mass：

134.14

HScode：

2934999090

Characteristics

PSA：

XLogP3：

0.9

Density：

1.3±0.1 g/cm3

Boiling Point：

311.6°C at 760 mmHg

Flash Point：

142.2±20.4 °C

Refractive Index：

1.685

1,2-Benzisoxazol-6-amine Use and Manufacturing

A quantity of 0.13 g (1 mmole) OF BENZO [d] isoxazol-6-ylamine is treated with 0.27 g (1 mmole) of 6, 8-Dibromo-imidazo [1, 2-a] pyrazine in acetonitrile with 3 eq. OF K2C03 AT REFLUX for 16 hrs. The reaction mixture is cooled partitioned between ethyl acetate and water, the organic extracts are dried over anhydrous MGSO4 and evaporated in vacuo to afford Benzo [d] ISOXAZOL-6-YL- (6-BROMO- imidazo [1, 2-A] PYRAZIN-8-YL)-AMINE

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CAS No.: 828300-70-5

Grade: Industrial Grade

Content: 99%

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