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Home > Encyclopedia > Archaeosine

Archaeosine

Archaeosine structure

Archaeosine 

structure
  • CAS No:

    148608-52-0

  • Formula:

    C12H16N6O5

  • Chemical Name:

    Archaeosine

  • Synonyms:

    1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide,2-amino-4,7-dihydro-4-oxo-7-β-D-ribofuranosyl-;2-Amino-4,7-dihydro-4-oxo-7-β-D-ribofuranosyl-1H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide;Archaeosine;7-Formamido-7-deazaguanosine

  • Categories:

    Biochemical Engineering  >  Saccharides

Description

ChEBI: A 7-deazaguanine ribonucleoside having 7-formamidino-7-deazaguanine as the nucleobase. It is found in the majority of archaeal tRNAs specifically at position 15 of the dihydrouridine loop (D-loop), a position not modified in either eukaryotic or bacterial RNA.


Archaeosine is a 7-deazaguanine ribonucleoside having 7-formamidino-7-deazaguanine as the nucleobase. It is found in the majority of archaeal tRNAs specifically at position 15 of the dihydrouridine loop (D-loop), a position not modified in either eukaryotic or bacterial tRNA. It derives from a 7-formamidino-7-deazaguanine.

Archaeosine Basic Attributes

324.297

324.29

Characteristics

192

-3.5

>215 °C (decomp)

Drug Information

2-amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide

Computed Properties

Molecular Weight:324.29
XLogP3:-3.5
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:324.11821763
Monoisotopic Mass:324.11821763
Topological Polar Surface Area:192
Heavy Atom Count:23
Complexity:556
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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