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Home > Encyclopedia > 11-Azido-3,6,9-trioxaundecanoic Acid

11-Azido-3,6,9-trioxaundecanoic Acid

11-Azido-3,6,9-trioxaundecanoic Acid structure

11-Azido-3,6,9-trioxaundecanoic Acid 

structure
  • CAS No:

    172531-37-2

  • Formula:

    C8H15N3O5

  • Chemical Name:

    11-Azido-3,6,9-trioxaundecanoic Acid

  • Synonyms:

    11-Azido-3,6,9-trioxaundecanoic Acid;N3-PEG3-CH2COOH;Azido-PEG3-propionic acid;Azido-PEG3-CH2COOH;Azido-PEG3-CH2CO2H

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

PROTAC Linker 14 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 14 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

11-Azido-3,6,9-trioxaundecanoic Acid Basic Attributes

233.2218

233.10100

DTXSID70448112

Characteristics

79.4

0.3

1.4690-1.4730

Safety Information

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

H315

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Computed Properties

Molecular Weight:233.22
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:233.10117059
Monoisotopic Mass:233.10117059
Topological Polar Surface Area:79.4
Heavy Atom Count:16
Complexity:230
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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