1-(4-Benzoyl-1-piperazinyl)-1-propanone
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1-(4-Benzoyl-1-piperazinyl)-1-propanone
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CAS No:
314728-85-3
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Formula:
C14H18N2O2
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Chemical Name:
1-(4-Benzoyl-1-piperazinyl)-1-propanone
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Synonyms:
1-Propanone,1-(4-benzoyl-1-piperazinyl)-;Piperazine,1-benzoyl-4-(1-oxopropyl)-;1-(4-Benzoyl-1-piperazinyl)-1-propanone;DM 235;Sunifiram
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CAS No:
Description
Sunifiram (DM-235) is a piperazine derived ampakine-like drug which has nootropic effects in animal studies with significantly higher potency than piracetam.IC50 value: Target: in vitro: DM 232 and DM 235 are novel antiamnesic compounds structurally related to ampakines. The involvement of AMPA receptors in the mechanism of action of DM 232 and DM 235 was, therefore, investigated in vivo and in vitro. Both compounds (0.1 mg/kg i.p.) were able to reverse the amnesia induced by the AMPA re
Computed Properties
Molecular Weight:246.30
XLogP3:1.1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:246.136827821
Monoisotopic Mass:246.136827821
Topological Polar Surface Area:40.6
Heavy Atom Count:18
Complexity:303
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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1-(4-Benzoyl-1-piperazinyl)-1-propanone
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