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BAPTA

BAPTA structure

CAS No:
85233-19-8
Formula:
C22H24N2O10
Chemical Name:
BAPTA
Synonyms:
Glycine,N,N′-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-;N,N′-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine];1,2-Bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid;BAPTA;1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid;2-[2-[2-[2-[Bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid
Categories:
Organic Chemistry > Amides

Description

BAPTA is a specific chelator of Ca2+, suppresses intracellular reactive oxygen species (ROS) levels.

BAPTA is a polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene. It has a role as a chelator. It is a polyamino carboxylic acid and a tetracarboxylic acid.

BAPTA Basic Attributes

Molecular Weight：

476.43

Exact Mass：

476.43

UNII：

K22DDW77C0

DSSTox ID：

DTXSID30234432

HScode：

29225090

Characteristics

PSA：

174

XLogP3：

2.2

Appearance：

White to off-white Powder

Density：

1.5±0.1 g/cm3

Melting Point：

177-179 °C

Boiling Point：

766.6°C at 760 mmHg

Flash Point：

417.4±32.9 °C

Refractive Index：

1.657

Water Solubility：

soluble in water and sodium bicarbonate.soluble in dimethyl sulfoxide

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36-37/39

RTECS Number：

MC0423000

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)|Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)

MeSH Entry Terms：

1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid

BAPTA Use and Manufacturing

As calcium chelator; 19F labelled forms for measurement of intracellular calcium.

Computed Properties

Molecular Weight:476.4
XLogP3:2.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:15
Exact Mass:476.14309497
Monoisotopic Mass:476.14309497
Topological Polar Surface Area:174
Heavy Atom Count:34
Complexity:613
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Sodium hydroxide

Hydrogen

Ammonium hydroxide

Ethanol

Acetic acid

Dimethylformamide

Acetonitrile

Hydrochloric acid

Recommended Suppliers of BAPTA

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1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid

CAS No.: 85233-19-8

Content: 99.00%

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CAS No.: 85233-19-8

Grade: Pharmaceutical Grade

Content: 99%

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