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Home > Encyclopedia > 3-BOC-AMINO-PYRROLIDIN-2-ONE

3-BOC-AMINO-PYRROLIDIN-2-ONE

3-BOC-AMINO-PYRROLIDIN-2-ONE structure

3-BOC-AMINO-PYRROLIDIN-2-ONE 

structure
  • CAS No:

    99780-97-9

  • Formula:

    C9H16N2O3

  • Chemical Name:

    3-BOC-AMINO-PYRROLIDIN-2-ONE

  • Synonyms:

    3-BOC-AMINO-PYRROLIDIN-2-ONE;Carbamic acid, N-(2-oxo-3-pyrrolidinyl)-, 1,1-dimethylethyl ester;tert-Butyl (2-oxopyrrolidin-3-yl);tert-butyl N-(2-oxopyrrolidin-3-yl)carbamate

3-BOC-AMINO-PYRROLIDIN-2-ONE Basic Attributes

200.24

200.116089

DTXSID70400750

2933790090

Characteristics

67.4

0.4

1.1±0.1 g/cm3

192.1±24.8 °C

1.491

Safety Information

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

3-BOC-AMINO-PYRROLIDIN-2-ONE Use and Manufacturing

To a solution of 3-amino-pyrrolidin-2-one (39) (2.8 g, 28 mmol) in [methanol:triethylamine (9:1)] (130 ml), was added di-tert-butyldicarbonate (6.7 g, 30.8 mmol). Into a 100 mL 3-necked round-bottom flask purged and maintained under an inert atmosphere of nitrogen, was placed a solution of 1.2 (2 g, 19.98 mmol, 1.00 equiv) in MeOH (30 mL) and Et

Computed Properties

Molecular Weight:200.23
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:200.11609238
Monoisotopic Mass:200.11609238
Topological Polar Surface Area:67.4
Heavy Atom Count:14
Complexity:245
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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