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BNP-32 (HUMAN)

BNP-32 (HUMAN) structure

CAS No:
124584-08-3
Formula:
C143H244N50O42S4
Chemical Name:
BNP-32 (HUMAN)
Synonyms:
Nesiritide [USAN:INN];H-SER-PRO-LYS-MET-VAL-GLN-GLY-SER-GLY-CYS-PHE-GLY-ARG-LYS-MET-ASP-ARG-ILE-SER-SER-SER-SER-GLY-LEU-GLY-CYS-LYS-VAL-LEU-ARG-ARG-HIS-OH;H-SER-PRO-LYS-MET-VAL-GLN-GLY-SER-GLY-CYS-PHE-GLY-ARG-LYS-MET-ASP-ARG-ILE-SER-SER-SER-SER-GLY-LEU-GLY-CYS-LYS-VAL-LEU-ARG-ARG-HIS-OH (DISULFIDE BRIDGE: 10-26);BRAIN NATRIURETIC PEPTIDE (1-32), HUMAN;BRAIN(B-TYPE) NATRIURETIC PEPTIDE-32 (HUMAN);BRAIN NATRIURETIC PEPTIDE, HUMAN;BRAIN NATRIURETIC PEPTIDE-32 (HUMAN);B-TYPE (BRAIN) NATRIURETIC PEPTIDE-32 (HUMAN)
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Nesiritide was introduced in the US as a new intravenous treatment for patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. Nesiritide is the first human recombinant form of the potent vasodilatory B-type natriuretic peptide (also known as brain natriuretic peptide), a naturally occurring 32 amino acid peptide with a disulfide-bonded 17 amino acid ring structure.

BNP-32 (HUMAN) Basic Attributes

Molecular Weight：

3464.04

Exact Mass：

3461.737793

EC Number：

1312995-182-4

Characteristics

PSA：

1613.94000

XLogP3：

-16.34

Appearance：

powder

Density：

1.52±0.1 g/cm3(Predicted)

Refractive Index：

1.679

Water Solubility：

Soluble in water at 1mg/ml

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

EE1534000

BNP-32 (HUMAN) Use and Manufacturing

Treatment of congestive heart failure (renin-angiotensin system antagonist).

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