3-Bromo-5-methylphenol
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3-Bromo-5-methylphenol
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CAS No:
74204-00-5
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Formula:
C7H7BrO
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Chemical Name:
3-Bromo-5-methylphenol
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Synonyms:
5-Bromo-3-methylphenol;3-Bromo-5-hydroxytoluene;5-Bromo-3-hydroxytoluene;Phenol,3-broMo-5-Methyl-;3-methyl-5-bromophenol
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CAS No:
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
3-Bromo-5-methylphenol Use and Manufacturing
In a three-necked flask, 3-methyl 5-bromophenylboronic acid (15.0 g, 69.8 mmol) was added to potassium hydroxide (11.8 g, 209.4 mmol) aqueous solution (100 mL) was slowly added 30percent hydrogen peroxide solution (57.0 mL) and reacted at room temperature for 20 min.After completion, 2 mol/L dilute hydrochloric acid was adjusted to pH=7, extracted with dichloromethane (50 mL×3), dried over anhydrous sodium sulfate, and filtered.The solvent was evaporated under reduced pressure to give 3-methyl-5-bromophenol as an oily liquid, 11.3 g, with a yield of 86.5percentTo a solution of
Computed Properties
Molecular Weight:187.03
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:185.96803
Monoisotopic Mass:185.96803
Topological Polar Surface Area:20.2
Heavy Atom Count:9
Complexity:94.9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
