 Home > Encyclopedia > 8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)-

8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)-

8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)- structure

CAS No:
29025-14-7
Formula:
C28H38NO4.Br
Chemical Name:
8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)-
Synonyms:
8-Azoniabicyclo[3.2.1]octane,8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-,bromide (1:1),(3-endo)-;1αH,5αH-Tropanium,8-(p-butoxybenzyl)-3α-hydroxy-,bromide,(-)-tropate;8-Azoniabicyclo[3.2.1]octane,8-[(4-butoxyphenyl)methyl]-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-,bromide,[3(S)-endo]-;N-(Butoxybenzyl)hyoscyamine bromide;(p-Butoxybenzyl)hyoscyaminium bromide;Butropium bromide;Coliopan;BHB

Request for Quotation

Description

Crystalline Solid

Butropium bromide is an organic bromide salt of butropium. It is a drug which suppresses spasm of smooth muscles of internal organs, inhibits gastric acid secretion and relieves abdominal pain. It is used in the treatment of spasmodic pains associated with gastritis, gastric ulcers and cholelithiasis. It has a role as an antispasmodic drug and a muscarinic antagonist. It is an organic bromide salt and a quaternary ammonium salt. It contains a butropium.

8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)- Basic Attributes

Molecular Weight：

532.515

Exact Mass：

531.19800

EC Number：

249-375-4

UNII：

R3K4503MV7

DSSTox ID：

DTXSID1022716

Characteristics

PSA：

55.76000

XLogP3：

1.78760

Melting Point：

166-168 °C

Toxicity：

Peritoneal-rat LD50: 113 mg/kg; oral-mouse LD50: 1500 mg/kg

Flammability characteristics：

Thermal decomposition releases toxic nitrogen oxides and bromide fumes

Specific rotation：

D20 -21.7° (c = 0.5 in water)

Safety Information

Storage features：

Warehouse ventilated, low temperature and dry

Toxicity

Toxicity class：

moderately toxic

Drug Information

MeSH Entry Terms：

butoxybenzyl hyoscyamine

8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)- Use and Manufacturing

Anticholinergic. Antispasmodic.

Computed Properties

Molecular Weight:532.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:531.19842
Monoisotopic Mass:531.19842
Topological Polar Surface Area:55.8
Heavy Atom Count:34
Complexity:597
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Learn More Other Chemicals

Hot Searches: subperiosteal abscess; aluminum polyphosphate; h2sio3 ra sio2; teaa; common peroneal injury; dimethyl terephthalate drug

Guide of 8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)-

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

8-Azoniabicyclo[3.2.1]octane, 8-[(4-butoxyphenyl)methyl]-3-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-8-methyl-, bromide (1:1), (3-endo)-

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.