5-Carboxy-X-rhodamine
-
5-Carboxy-X-rhodamine
structure -
-
CAS No:
216699-35-3
-
Formula:
C33H30N2O5
-
Chemical Name:
5-Carboxy-X-rhodamine
-
Synonyms:
1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j′]diquinolizin-18-ium,9-(2,4-dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-,inner salt;5-Carboxy-X-rhodamine;5-ROX;Red 5-ROX;1073190-57-4;2316424-92-5
-
CAS No:
Description
5-ROX is a pure-5 isomer derived from carboxy-X-rhodamine. 5-ROX is a fluorescent oligonucleotide marker, acts as a donor molecule in FRET imaging coupled with porphyrins.5-ROX is widely used for oligonucleotide labeling and automated DNA sequencing applications.Excitation:575nm. Emission:575nm
5-carboxy-X-rhodamine is an X-rhodamine compound having a carboxy substituent at the 5-position. It has a role as a fluorochrome. It derives from a hydride of a 2,3,6,7,12,13,16,17-octahydropyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-18-ium.
Safety Information
36/37/38
26
Xi
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
5-Carboxy-X-rhodamine Use and Manufacturing
5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties
Computed Properties
Molecular Weight:534.6
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:534.21547206
Monoisotopic Mass:534.21547206
Topological Polar Surface Area:92.9
Heavy Atom Count:40
Complexity:1200
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes