2-Chloro-5-(trifluoroMethoxy)pyridine

2-Chloro-5-trifluoromethoxypyridine (6); 2-Chloro-5-trichloromethoxypyridine (5, 7.4 g, 30.0 mmol) is added dropwise to a molten mixture of SbFStep 1: (0630) To antimony trifluoride (4.05 g, 23 mmol) and antimony pentachloride (0.22 mL, 1.7 mmol) at 120° C. was added the trichloromethyl ether prepared in step 1 of scheme 25 (2.80 g, 11 mmol). The reaction was warmed to 165° C. under nitrogen and stirred for 14 h and then warmed to 175° C. and stirred for an additional 4 h. The reaction was cooled to room temperature. The resulting solid mass was stirred vigorously with saturated NaHCO

Molecular Weight:197.54
XLogP3:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:196.9855259
Monoisotopic Mass:196.9855259
Topological Polar Surface Area:22.1
Heavy Atom Count:12
Complexity:152
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes