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Transplatin

Transplatin structure

CAS No:
14913-33-8
Formula:
Cl2H6N2Pt
Chemical Name:
Transplatin
Synonyms:
Platinum,diamminedichloro-,(SP-4-1)-;Platinum,diamminedichloro-,trans-;(SP-4-1)-Diamminedichloroplatinum;trans-Diamminedichloroplatinum;trans-Dichlorodiammineplatinum(II);trans-Platinum(II) ammonium chloride;trans-Platinumdiammine dichloride;trans-Diamminedichloroplatinum(II);trans-Dichlorodiammine platinum;trans-Dichlorodiamineplatinum(II);Transplatin;trans-Diaminedichloroplatinum;trans-DDP;NSC 131558;82847-81-2;64658-56-6
Categories:
Catalyst and Auxiliary > Precious Metal Catalysts

Description

Yellow Powder or CrystalChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.

Transplatin Basic Attributes

Molecular Weight：

300.05

Exact Mass：

298.955597

EC Number：

239-733-8

HScode：

28439000

Characteristics

PSA：

XLogP3：

2.02430

Appearance：

yellow crystalline

Density：

3.746 g/cm3

Melting Point：

340 °C (dec.)(lit.)

Refractive Index：

1.706

Water Solubility：

Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water.

Safety Information

Packing level：

Hazard category：

6.1(a)

Transport codes：

UN 3288 6.1/PG 2

wgk germany：

hazard class code：

45-25-41-68-42/43-40-23/24/25

safety instructions：

53-26-39-45-36/37-24-23

RTECS Number：

TP2455000

Marks：

T,Xn

Precautionary statement(s)：

P261-P280-P284-P304 + P340-P305 + P351 + P338 + P310

Hazard Statements：

H317-H318-H334

Transplatin Use and Manufacturing

Transplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.

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