 Home > Encyclopedia > Clozapine N-oxide

Clozapine N-oxide

Clozapine N-oxide structure

CAS No:
34233-69-7
Formula:
C18H19ClN4O
Chemical Name:
Clozapine N-oxide
Synonyms:
5H-Dibenzo[b,e][1,4]diazepine,8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-;5H-Dibenzo[b,e][1,4]diazepine,8-chloro-11-(4-methyl-1-piperazinyl)-,N-oxide;8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine;Clozapine N-oxide
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

Clozapine N-oxide (CNO) is a major metabolite of the anti-psychotic drug clozapine. Clozapine N-oxide is a agonist for the chemogenetic Designer Receptors Exclusively Activated by Designer Drug (DREADD) system.

Clozapine N-oxide Basic Attributes

Molecular Weight：

342.82

Exact Mass：

342.82

HScode：

29335990

Characteristics

PSA：

45.7

XLogP3：

0.76

Density：

1.36g/cm3

Melting Point：

190-248°C

Boiling Point：

517.4ºC at 760mmHg

Flash Point：

9℃

Refractive Index：

1.685

Water Solubility：

soluble in DMSO.

Storage Conditions：

-20°C Freezer, Under Inert Atmosphere

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

UN 2811 6.1/PG 3

wgk germany：

hazard class code：

22-36/37/38-39/23/24/25-23/24/25-11

safety instructions：

26-36-45-36/37-16-7

RTECS Number：

HP1760000

Marks：

Xn,T,F

Precautionary statement(s)：

P261-P301 + P310-P305 + P351 + P338

Hazard Statements：

H301-H315-H319-H335

Clozapine N-oxide Use and Manufacturing

A 5-HT2 antagonist.A major metabolite of clozapine that can be monitored by HPLC.Possesses little or no activity towards serotonin receptors

Recommended Suppliers of Clozapine N-oxide

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Clozapine N-oxide

CAS No.: 34233-69-7

Content: 99.00%

Inquiry
REFSYN BIOSCIENCES PVT LTD Contact Supplier

IN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Drug Impurity

Clozapine N Oxide

CAS No.: 34233-69-7

Inquiry