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Corynoxine B

Corynoxine B structure

CAS No:
17391-18-3
Formula:
C22H28N2O4
Chemical Name:
Corynoxine B
Synonyms:
Corynoxine B;7-Isocorynoxine
Categories:
Chemical Reagents > Organic Reagents

Description

Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese); a Beclin-1-dependent autophagy inducer. IC50 value:Target: Autophagy inducerin vitro: Corynoxine B, a natural autophagy inducer, restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA, which may be attributed to its ability to block SNCA-HMGB1 interaction [1].in vivo: Corynoxine B exhibited prolongation of the thiopental-induced hypnosis

Corynoxine B Basic Attributes

Exact Mass：

384.204895

Characteristics

PSA：

67.87000

XLogP3：

3.31

Density：

1.23±0.1 g/cm3(Predicted)

Boiling Point：

560.8±50.0 °C(Predicted)

Flash Point：

293.0±30.1 °C

Refractive Index：

1.596