2,8-Dibromoquinoline

Step 2C: Preparation of 2, 8-dibromoquinolme:; A mixture of 8-bromoquinolin-2(lH)-one (5 g, 22 mmol) and phosphoryl tribromide (13 g, 45 mmol) was heated to 140°C for three hours. The resulting mixture was poured onto 100 g of ice and 100 ml water. The mixture was stirred for 1 hour and the resulting solids were filtered to yield the title compound. (5.1 g, 80 percent yield) MS APCI (+) 286, 288, and 290 (M+l of each isotope combination) detected.A mixture of 8-bromoquinolin-2(lH)-one (5 g, 22 mmol) and phosphoryl tribromide (13 g, 45 mmol) was heated to 140°C for three hours. The resulting mixture was poured onto 100 g of ice and 100 ml water. The mixture was stirred for 1 hour and the resulting solids were filtered to yield the title compound. (5.1 g, 80 percent yield) MS APCI (+) 286, 288, and 290 (M+l of each isotope combination) detected.

Molecular Weight:286.95
XLogP3:3.9
Hydrogen Bond Acceptor Count:1
Exact Mass:286.87682
Monoisotopic Mass:284.87887
Topological Polar Surface Area:12.9
Heavy Atom Count:12
Complexity:163
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes