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Home > Encyclopedia > 3,4-dehydrochlorambucil

3,4-dehydrochlorambucil

3,4-dehydrochlorambucil structure

3,4-dehydrochlorambucil 

structure
  • CAS No:

    73027-06-2

  • Formula:

    C15H19Cl2NO2

  • Chemical Name:

    3,4-dehydrochlorambucil

  • Synonyms:

    3,4-dehydrochlorambucil;3,4-deshydrochlorambucil;(E)-4-[4-[bis(2-chloroethyl)amino]phenyl]but-3-enoic acid;(E)-4-[4-[Bis(2-chloroethyl)amino]phenyl]-3-butenoic Acid;CHEBI:165233;((e)-4-[4-bis(2-chloroethyl)aminophenyl]3-butenoic acid);3-Butenoic acid, 4-(4-(bis(2-chloroethyl)amino)phenyl)-, (E)-

Description

3,4-Dehydrochlorambucil is a member of styrenes.

3,4-dehydrochlorambucil Basic Attributes

316.22286

301.064

Characteristics

40.5

3.3

1.284±0.06 g/cm3(Predicted)

490.2ºC at 760 mmHg

250.3ºC

1.61

Drug Information

3,4-dehydrochlorambucil

3,4-dehydrochlorambucil Use and Manufacturing

(E)-4-[4-[Bis(2-chloroethyl)amino]phenyl]-3-butenoic Acid is a metabolite of Chlorambucil (C325050), a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia.

Computed Properties

Molecular Weight:302.2
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:301.0636342
Monoisotopic Mass:301.0636342
Topological Polar Surface Area:40.5
Heavy Atom Count:19
Complexity:283
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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