Ac-rC Phosphoramidite
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Ac-rC Phosphoramidite
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CAS No:
121058-88-6
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Formula:
C47H64N5O9PSi
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Chemical Name:
Ac-rC Phosphoramidite
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Synonyms:
DMT-2"O-TBDMS-rC(ac) Phosphoramidite;DMT-2"O-TBDMS-rC(ac) Phosphoramidite, configured for ABI;DMT-2"O-TBDMS-rC(ac) Phosphoramidite, configured for MerMade;SCHEMBL668064;Dmt-2"o-tbdms-rc(ac) amidite;ZINC170162862;DMT-2"O-TBDMS-rC(ac) Pharmadite(R);N-Acetyl-5"-O-(4,4-dimethoxytrityl)-2"-O-[(tert-butyl)dimethylsilyl]cytidine-3"-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;058D886;J-700107
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CAS No:
Ac-rC Phosphoramidite Use and Manufacturing
5' -O-DMT-2' -O-TBDMS-iV?-acetylcytosine 3' -O-(N, N-diisopropyl cyanoethyl phosphoramidite) was N-deprotected with aqueous ammonia in methanol. The product was dried well and treated with di-tert-butyl pyrocarbonate and potassium carbonate in THF. The product Boc RNA amidite was isolated by column chromatography. Likewise were prepared the fuliy protected 1V6- diBoc-adenosine, N2-Boc-guanosine, and N-i -Boc-uridine phosphoramidites.To the compound (E77) (755.6 mg) and [0353] To the compound (E23) (284.5 mg) and
Computed Properties
Molecular Weight:902.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:21
Exact Mass:901.42109217
Monoisotopic Mass:901.42109217
Topological Polar Surface Area:153
Heavy Atom Count:63
Complexity:1560
Defined Atom Stereocenter Count:4
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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