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Bromhexine hydrochloride

Bromhexine hydrochloride structure

CAS No:
611-75-6
Formula:
C14H20Br2N2.ClH
Chemical Name:
Bromhexine hydrochloride
Synonyms:
Benzenemethanamine,2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-,hydrochloride (1:1);Toluene-α,2-diamine,3,5-dibromo-Nα-cyclohexyl-Nα-methyl-,monohydrochloride;Benzenemethanamine,2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-,monohydrochloride;Bisolvon;Bisolvon hydrochloride;Cyclohexylmethyl(2-amino-3,5-dibromobenzyl)ammonium chloride;N-Cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)ammonium chloride;Bromhexine hydrochloride;Nα-Cyclohexyl-Nα-methyl-3,5-dibromotoluene-α,2-diamine hydrochloride;N-Cyclohexyl-N-methyl-N-(2-amino-3,5-dibromobenzyl)ammonium chloride;2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine monohydrochloride;Bromhexine chloride;Bromhexine monohydrochloride;Quentan;Auxit;Ophtosol;2,4-Dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline hydrochloride;2,4-Dibromo-6-[(cyclohexyl-methyl-amino)-methyl]-phenylamine hydrochloride
Categories:
Active Pharmaceutical Ingredients > Respiratory Drugs

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Description

White Solid

Bromhexine hydrochloride Basic Attributes

Molecular Weight：

412.59

Exact Mass：

411.974

EC Number：

210-280-8

HScode：

29215990

Characteristics

PSA：

29.3

XLogP3：

5.94150

Appearance：

White Solid

Melting Point：

237.5-289 °C (decomp)

Boiling Point：

441.5ºC at 760 mmHg

Flash Point：

220.8ºC

Storage Conditions：

2-8ºC

Safety Information

wgk germany：

hazard class code：

R20/21/22

safety instructions：

22-24/25-36-26

RTECS Number：

XS9950000

Marks：

Precautionary statement(s)：

P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P391, P403+P233, P405, P501

Hazard Statements：

H302

Bromhexine hydrochloride Use and Manufacturing

antibacterial Expectorant; mucolytic. Antimucolytic

Material

o-Toluidine

Drug Function and Efficacy

Expectorants can reduce the viscosity of bronchial mucus, making sputum thinner and easier to cough up

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound Chlorprenaline Houttuynia Sodium Tablets
Ingredients	Each tablet contains 4 mg of chlorprenaline hydrochloride, 4 mg of bromhexine hydrochloride, 20 mg of houttuynia cordata sodium, and 1.5 mg of chlorpheniramine maleate. The auxiliary materials are appropriate amounts of starch and dextrin.
Indication	1. Do not use with monoamine oxidase inhibitors (such as furazolidone, pargyline, etc.). 2. Do not use with other bronchodilator beta-2 receptor agonists. 3. Use with anticholinergics or theophylline drugs to enhance the effect of relieving asthma. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a physician or pharmacist for details.
Specifications	Compound
Manufacturer	Jilin Xianfeng Technical Pharmaceutical Co., Ltd.

Tulobuterol Hydrochloride Tablets
Ingredients	Tulobuterol hydrochloride, bromhexamine hydrochloride, promethazine hydrochloride, and appropriate amount of excipients.
Indication	It is well absorbed orally and the effective concentration in the blood can be maintained for 6 hours.
Specifications	0.5mg
Manufacturer	Xi`an Han Feng Pharmaceutical Co., Ltd.

Compound chlorprenaline and bromhexine tablets
Ingredients	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
Indication	1. It has an additive effect when used in combination with other bronchial β2 receptor agonists. 2. When this product is used in combination with other β2 receptor agonists, the efficacy is reduced and adverse reactions such as hand tremors and palpitations may be more obvious. 3. If used in combination with phosphodiesterase inhibitors such as theophylline or anticholinergic antiasthmatic drugs, its bronchial dilation and asthma relief effects are enhanced. 4. Bromhexine hydrochloride can increase the concentration of tetracycline antibiotics in the bronchi.
Specifications	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
Manufacturer	Zhejiang Dongri Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

株式会社三洋化学研究所

Japan
Active
China CHINO PHARMA Ltd

China
Active
China Resources Double-Crane Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

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