1-(1-Butoxy-2-propoxy)-2-propanol

190.280

190.28

249-951-5

1617

DTXSID8027959

Colorless liquid

29094990

38.69000

1.13

Liquid

0.9185 g/cm³ @ Temp: 20 °C

None; turns to glass at -43 °C

103 °C @ Press: 10 Torr

96.1±0.0 °C

1.434

0.24 M

Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water.

0.001 mm Hg at 30 °C

Relative vapor density (air = 1): 6.6

Molecular weight: approx 400; Specific gravity: approx 0.973 at 25/25 °C; Vapor pressure: <0.1 mm Hg at 25 °C; Solubility in water: 0.2 g/100 g at 20 °C /BPG 400/|Molecular weight: approx 800; Specific gravity: approx 0.990 at 25/25 °C; Vapor pressure: <0.1 mm Hg at 25 °C; Solubility in water: 0.1 g/100 g at 20 °C /BPG 800/

194 °C

II

5.1

UN 3087 5.1/PG 2

1

R8:Contact with combustible material may cause fire. R25:Toxic if swallowed. R26:Very Toxic by inhalation. R34:Causes burns.

S17:Keep away from combustible material . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . S36/37/39:

UA8200000

O,T+,T

Stable. Combustible. Incompatible with strong oxidizing agents.

SRP: Criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|Safe Disposal of Pesticides. The best way to dispose of small amounts of excess pesticides is to use them - apply them - according to the directions on the label. If you cannot use them, ask your neighbors whether they have a similar pest control problem and can use them. If all of the remaining pesticide cannot be properly used, check with your local solid waste management authority, environmental agency, or health department to find out whether your community has a household hazardous waste collection program or a similar program for getting rid of unwanted, leftover pesticides. These authorities can also inform you of any local requirements for pesticide waste disposal.|Safe Disposal of Pesticides. An empty pesticide container can be as hazardous as a full one because of residues left inside. Never reuse such a container. When empty, a pesticide container should be rinsed carefully three times and the rinsewater thoroughly drained back onto the sprayer or the container previously used to mix the pesticide. Use the rinsewater as a pesticide, following label directions. Replace the cap or closure securely. Dispose of the container according to label instructions. Do not puncture or burn a pressurized container like an aerosol - it could explode. Do cut or puncture other empty pesticide containers made of metal or plastic to prevent someone from reusing them. Wrap the empty container and put it in the trash after you have rinsed it.

USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Polypropylene Glycol. EPA 738-R-07-015 (September 25, 2007). The RED summarizes the risk assessment conclusions and outlines any risk reduction measures necessary for the pesticide to continue to be registered in the U.S.[Available from, as of October 7, 2009: http://www.epa.gov/pesticides/reregistration/status.htm]

Combustible.

|Warning|H302 (38.46%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, and P501|Aggregated GHS information provided by 1452 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Danger|H318 (30.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]|P260, P261, P264, P271, P280, P284, P304+P312, P304+P340, P305+P351+P338, P310, P312, P320, P337+P313, P403+P233, P405, and P501|Aggregated GHS information provided by 1570 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]|P260, P314, and P501

In case of fire in the surroundings, use appropriate extinguishing media.

For liquid concentrate applications, mixers, loaders, applicators, and other handlers must wear: Long-sleeved shirt and long pants, Shoes plus socks, and Chemical-resistant gloves.|For all ready-to-use formulations (including pour-ons, repellent sticks, rollons, trigger sprayers, aerosol sprayers) except impregnated wipes, applicators and other handlers must wear: Long-sleeved shirt and long pants and Shoes plus socks.

Explosive limits , vol% in air: 0.6-20.4

Do not discharge effluent containing this product into lakes, streams, ponds, estuaries, oceans, or other waters unless in accordance with the requirements of a National Pollution Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge. Do not discharge effluent containing this product to sewer systems without previously notifying the local sewage treatment plant authority. For guidance contact your State Water Board or Regional Office of the EPA.|If a spill occurs, clean it up promptly. Don't wash it away. Instead, sprinkle the spill with sawdust, vermiculite, or kitty litter. Sweep it into a plastic garbage bag, and dispose of it as directed on the pesticide product label.|After Applying a Pesticide, Indoors or Outdoors. To remove pesticide residues, use a bucket to rinse tools or equipment three times, including any containers or utensils that you used when mixing the pesticide. Then pour the rinsewater into the pesticide sprayer and reuse the solution by applying it according to the pesticide product label directions. After applying any pesticide wash your hands and any other parts of your body that may have come in contact with the pesticide..To prevent tracking pesticides inside, remove or rinse your boots or shoes before entering your home. Wash any clothes that have been exposed to a lot of pesticide separately from your regular wash.

SRP: Studies of the safety of contact lens use by industrial workers reach conflicting conclusions. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|SRP: Contaminated protective clothing should be segregated in a manner that results in no direct personal contact by personnel who handle, dispose of, or clean the clothing. Quality assurance procedures to confirm the efficacy of the cleaning procedures should be implemented prior to the decontaminated protective clothing being returned for reuse by the workers. Contaminated clothing (including shoes/socks) should not be taken home at end of shift, but should remain at employee's place of work for cleaning.|Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.|Users should wash hands before eating, drinking, chewing gum, using tobacco, or using the toilet.|For more Preventive Measures (Complete) data for Butoxypolypropylene glycol (14 total), please visit the HSDB record page.

Minor eye and skin irritant.|A skin irritant.

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Then wash away with plenty of water.

Separated from strong oxidants.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

NO open flames. NO contact with strong oxidizing agents.

Use ventilation.

Protective gloves.

Wear safety spectacles.

Stabilene is ... used as a synergist for pyrethrins and allethrin, and improves the effectiveness of residual toxicants.

LD50 Rat oral was 34.5 ml/kg.|LD50 Rat oral 9100 mg/kg|LD50 Rat (male) oral 5.84 g/kg /BPG 400/|LD50 Rat (male) oral 9.16 g/kg /BPG 800/|For more Non-Human Toxicity Values (Complete) data for Butoxypolypropylene glycol (12 total), please visit the HSDB record page.

Butoxypolypropylene's production may result in its release to the environment through various waste streams; its use as an insect repellent(1) will result in its direct release to the environment(SRC).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 28,325 workers (3,407 of these were female) were potentially exposed to butoxypolypropylene glycol in the US(1). The NOES Survey does not include farm workers. Occupational exposure to butoxypolypropylene glycol may occur through dermal contact with this compound at workplaces where butoxypolypropylene glycol is produced or used(SRC).

3 = moderately toxic: probable oral lethal dose (human) 500 mg-5 g/kg, between 1 oz and 1 pint (or 1 lb) for 70 kg person (150 lb). /Butoxy propylene glycols/

Groups of 3 female rats/time interval were administered single doses of 14C - labeled BPG in corn oil ranging from 18-22 mg/rat either orally (via gavage) or dermally (applied to a 2 cm x 3 cm area of the back and held in place for 6 hours). Following dosing, the rats were housed in metabolism cages for collection of urine, feces, CO2, and tissues for 6, 24, or 96 hours. Based on data from 96 hours collection period, amount of radioactivity absorbed following oral and dermal dosing was 58.7% and 12%, respectively. Following the oral administration, the amount of radioactivity found as percent of administered dose of BPG was 35.2%, 41%, 3.3%, and 20.2% in urine, feces, tissues, and expired CO2, respectively. Following the dermal administration, the amount of radioactivity found as percent of dose was 2.8%, 1.4%, 6.1%, and1.4% in urine, feces, tissues, and expired CO2, respectively.

Fresh air, rest.

Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Ethylene glycol, glycols, and related compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Ethylene glycol, glycols, and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ethylene glycol, glycols, and related compounds/

/CASE REPORTS/ In 2002, a woman in Oklahoma was hospitalized after using Pyranha fly spray on horses. Her face was distorted, and her words slurred. She reportedly had leg problems, tremors, memory problems. The medical toxicologist's conclusion was that the patient, a professional horse trainer, developed a complex neurotoxic movement disorder following sensitization to Pyranha that contains ... 33% /butoxypolypropylene glycol/ BPG.

Butoxypolypropylene glycol was the most commonly used insecticide on other livestock (hogs, sheep, equine and goats), at 31.1 thousand pounds.

Alleviate Stabilene Horse Insecticide: Active Ingredients 0.11% d-trans-Allethrin , 15.00% Butoxypolypropylene glycol, 1.00% Piperonyl butoxide|Farnam Crash! Wipe-On Insecticide/Repellent: Active Ingredients 4.85% Butoxypolypropylene glycol , 0.50% Dipropyl isocinchomeronate, 1.63% Piperonyl butoxide, 0.20% Pyrethrins , 0.15% Cypermethrin|Adams Equine Residual Fly Mist/Wipe: Active Ingredient 5.000% Butoxypolypropylene glycol , 1.000% Dipropyl isocinchomeronate, 2.004% N-Octyl bicycloheptene dicarboximide, 0.500% Piperonyl butoxide, 1.000% Pyrethrins, 0.208% Permethrin, mixed cis,trans|Farnam X-5303-98: Active Ingredients 5.00% Butoxypolypropylene glycol, 1.00% Dipropyl isocinchomeronate, 2.00% N-Octyl bicycloheptene dicarboximide, 0.50% Piperonyl butoxide, 0.20% Permethrin, mixed cis,trans, 0.13% Prallethrin|For more Formulations/Preparations (Complete) data for Butoxypolypropylene glycol (43 total), please visit the HSDB record page.

Adhesive manufacturing|2-Propanol, 1-(2-butoxy-1-methylethoxy)-: ACTIVE|There are 2 active ingredients in reregistration case 3123 for polypropylene glycol. The RED evaluates the only active ingredient in this case with currently registered products; therefore, only butoxypolypropylene glycol (BPG), PC Code 011901/CAS No. 9003-13-8, 57 active products as of September, 2001 / was assessed. The other active ingredient in this case /poly(oxy(methyl-1,2ethanediyl)), alpha-hydro-omegahydroxy,CAS No. 25322-69-4 / has no product registrations /last pesticide product cancelled October 10, 1989/ and is not being supported for reregistration. This active ingredient would be evaluated only if and when new registration applications were to be submitted for new products.|Products and formulations that contain Butoxypolypropylene glycol (BPG) have a combination of other active ingredients; pyrethrins and piperonyl butoxide are typical, although other potential combinations include a variety of synthetic pyrethroids.|... first registered by FMC in 1960. Bayer Environmental Science is currently the sole technical registrant... 57 active products as of September 2007. Being supported for reregistration.

EPA Safer Chemical Functional Use Classes -> Solvents|Safer Chemical Classes -> Yellow triangle - The chemical has met Safer Choice Criteria for its functional ingredient-class, but has some hazard profile issues|Cosmetics -> Antistatic; Emollient; Skin conditioning; Surfactant|FLY REPELLENTS