AR-13324 (mesylate)
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AR-13324 (mesylate)
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CAS No:
1422144-42-0
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Formula:
C30H35N3O9S2
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Chemical Name:
AR-13324 (mesylate)
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Synonyms:
Netarsudil Dimesylate;AR-13324 (mesylate);Netarsudil Mesylate;Benzoic acid, 2,4-dimethyl-, [4-[(1S)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl]phenyl]methyl ester, methanesulfonate (1:2)
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CAS No:
Drug Information
Roclanda is indicated for the reduction of elevated intraocular pressure (IOP) in adult patients with primary open-angle glaucoma or ocular hypertension for whom monotherapy with a prostaglandin or netarsudil provides insufficient IOP reduction.
AR-13324 (mesylate) Use and Manufacturing
Human drugs -> Roclanda -> EMA Drug Category|Ophthalmologicals -> Human pharmacotherapeutic group|Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:645.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:8
Exact Mass:645.18147205
Monoisotopic Mass:645.18147205
Topological Polar Surface Area:220
Heavy Atom Count:44
Complexity:770
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
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