Maropitant citrate hydrate
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Maropitant citrate hydrate
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CAS No:
359875-09-5
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Formula:
C38H48N2O8
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Chemical Name:
Maropitant citrate hydrate
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Synonyms:
ACIDUM CITRICUM ANHYDRICUM;2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID;B-HYDROXYTRICARBALLYLIC ACID;HYDROXYTRICARBALLYLIC ACID;FEMA 2306;CEFIXIM TELLURITE SUPPLEMENT;CITRATE ION CHROMATOGRAPHY STANDARD;CT SUPPLEMENT
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CAS No:
Description
Maropitant Citrate is a neurokinin receptor antagonist with antiemetic activity. This agent is approved for veterinary use only.
Maropitant citrate hydrate is a specific neurokinin-1 (NK-1) receptor antagonist that selectively inhibits the production of substance P, a mediator involved in signalling vomiting. Maropitant citrate was therefore originally used to treat vomiting in dogs and cats. Currently, it is also used as an adjunct to visceral analgesia in dogs and cats, and in other species such as horses and birds.
Maropitant citrate hydrate Basic Attributes
660.81
678.35163118
201-069-1
LXN6S3999X
C78028
QA04AD90
Safety Information
1
Xi,T
26-39-45-36/37-22
GE7350000
41-42/43-36/37/38-25
UN 3284 6.1/PG 3
|Danger|H317 (50%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P260, P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P310, P314, P321, P333+P313, P337+P313, P363, P391, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Tablets Dogs:For the prevention of nausea induced by chemotherapy.For the prevention of vomiting induced by motion sickness.For the prevention and treatment of vomiting, in conjunction with Cerenia solution for injection and in combination with other supportive measures.Solution for injectionDogs:For the treatment and prevention of nausea induced by chemotherapy.For the prevention of vomiting except that induced by motion sickness.For the treatment of vomiting, in combination with other supportive measures.For the prevention of perioperative nausea and vomiting and improvement in recovery from general anaesthesia after use of the μ-opiate receptor agonist morphine.Cats:For the prevention of vomiting and the reduction of nausea, except that induced by motion sickness.For the treatment of vomiting, in combination with other supportive measures.
Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)
(2S,2S)-2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine citrate monohydrate
Maropitant citrate hydrate Use and Manufacturing
Anti-emetic.
Veterinary drugs -> Cerenia -> EMA Drug Category|Alimentary tract and metabolism -> Veterinary pharmacotherapeutic group
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