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Sodium hydroxide

pharmaceutical raw materials
Sodium hydroxide structure

Sodium hydroxide 

structure
  • CAS No:

    1310-73-2

  • Formula:

    HNaO

  • Chemical Name:

    Sodium hydroxide

  • Synonyms:

    Sodium hydroxide (Na(OH));NaOH;Sodium hydroxide;Caustic soda;White caustic;Ascarite;Collo-Grillrein;Collo-Tapetta;Aetznatron;Soda,caustic;GR;GR (alkali reagent);NSC 135799;E 33;E 33 (degreasing agent);MO 67;FC 4370;StamperPrep;Tosoh Pearl;DL α;Promoter 3308B;ma-D 331;BO-200B;Caustic Solution 70TW;Reasol;S/4920/AP1;8012-01-9;1418731-95-9;2319645-49-1;2391974-94-8

  • Categories:

    Cosmetic Ingredient  >  Buffering

Description

Colorless to white, odorless solid (flakes, beads, granular form).

Sodium hydroxide Basic Attributes

39.99710

39.99250

923-604-4

2815110000

Characteristics

23.06000

-0.17680

Non white solid

2.13 g/cm3 @ Temp: 25 °C

323 °C

1388 °C

N/A

1.473-1.475

H2O: 418 g/L (0 °C), 1110 g/L (20 °C), 3370 g/L (100 °C);soluble in methanol and glycerol, negligible in ammonia, insoluble in ether

Storage Room low temperature ventilation drying ,Separate storage of flammable, combustible, and acids

24.5mmHg at 25°C

<1 (vs air)

Noncombustible Solid, but when in contact with water may generate sufficient heat to ignite combustible materials.

... Odorless ...

Detection - the minimum physical intensity detection by a subject where he or she is not required to identify the stimulus but just detect the existence of the stimulus - in water: 8.00X10-3 mol/L.

Strongly alkaline (1 % solution)

Safety Information

II

8

UN 1824 8/PG 2

1

R35

S26-S45-S37/39-S24/25-S36/37/39

TT2975000

C

Separated from food and feedstuffs, strong acids and metals. Store only in original container. Dry. Well closed. Store in an area without drain or sewer access.

CONTAINERS OF LYE MUST BE TIGHTLY CLOSED TO PREVENT CONVERSION TO SODIUM CARBONATE BY CARBON DIOXIDE OF AIR.

P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

H290-H314

Sodium hydroxide Use and Manufacturing

Methods of Manufacturing

Industrial caustic soda production methods are caustic and electrolytic methods are two. Caustic process according to different raw materials into Caustic soda caustic soda and caustic soda; electrolysis can be divided into membrane electrolysis and ion exchange membrane method.
1. Caustic soda method Soda ash, lime, respectively, by the alkali solution made of soda ash, made of lime milk, in 99 ~ 101 ℃ for caustic reaction, caustic liquor by clarification, evaporation and concentration to 40% or more, the system Get liquid caustic soda. The concentrated liquid is further boiled and solidified to obtain solid caustic soda product. Caustic mud with water washing, washing water for alkali.
2. Trona caustic soda Taken by crushing, dissolved (or alkali halogen), clarified after adding lime milk in the 95 ~ 100 ℃ for causticizing, caustic liquor by clarification, evaporation concentration to 46% NaOH concentration, clear Liquid cooling, salt and further boil after thickening. So as to obtain solid caustic soda product. The caustic mud is washed with water and the washing water is used to dissolve the trona. Sodium chloride or barium chloride refined to remove calcium, magnesium, sulfate ions and other impurities, and then in the clarification tank by adding sodium or caustic soda bran to accelerate the precipitation of sand, the sand After adding hydrochloric acid and filtering, the brine is sent to electrolysis after preheating, the electrolyte is preheated, evaporated, divided into salt and cooled to obtain liquid caustic soda, and further boiled to obtain solid caustic soda product. Salt water for salt washing.
3. Ion-exchange membrane method After the original salt of salt by the traditional method of refining, a fine salt water through the microporous sintered carbon filter tube filter, and then through the chelating ion exchange resin tower for secondary refining, So that the salt water calcium and magnesium content down to 0.002% or less, the secondary refined brine electrolysis, in the anode chamber to generate chlorine gas, anode chamber salt water Na + through the membrane into the cathode chamber and cathode chamber 0H generated sodium hydroxide, H + directly Discharge in the cathode to generate hydrogen. During the electrolysis, an appropriate amount of high purity hydrochloric acid was added to the anode chamber to neutralize the returned OH-. The pure water was added to the cathode chamber. In the cathode chamber generated high purity caustic soda concentration of 30% to 32% (mass), can be directly used as liquid caustic soda products, can also be further boil concentrated, in the system of body products. Its sodium hydroxide purification methods: sodium hydroxide contains impurities are usually iron, sodium chloride, silicate, carbonate and so on. Take 100g of industrial sodium hydroxide dissolved in 1L anhydrous ethanol (excluding acetaldehyde), in the absence of carbon dioxide, moisture, dry air filtration, removal of chloride, carbonate, silicate and other impurities, concentrated filtrate removal Ethanol, and the resulting solid sodium ethoxide was separated with concentration. Pure ethanol washed several times, a long time heating to remove the residual pressure of ethanol, the purity of about 99.8% sodium hydroxide. Electrolysis and causticization are adopted. Electrolysis method is divided into mercury electrolysis and diaphragm electrolysis. Mercury electrolysis salt salt, add soda ash, caustic soda and barium chloride to remove tungsten, magnesium and sulfate and other impurities. After clarification, sand filtration, hydrochloric acid, and then by preheating, electrolysis derived. Diaphragm electrolysis method is to salt, add soda ash, caustic soda and barium chloride, remove tungsten, magnesium and sulfate derived.

Uses

1. Basic and important chemical feed, used as textiles industry, printing, detergent, paper-making, soap-mak inmetallurgy, glass enamel, medica mentoil-refining and making synthetic fiber, plastics, and many kinds of organic-mediacy.
2. Choline acetyltransferase substrate.
3. Used as alkalimetric titrant, buffers, pH modifiers.

Computed Properties

Molecular Weight:39.997
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:39.99250893
Monoisotopic Mass:39.99250893
Topological Polar Surface Area:1
Heavy Atom Count:2
Complexity:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Price Analysis

Make your Sodium hydroxide purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Sodium hydroxide prices .
  • Data: 2026-08-21
  • Price: 986.23Yuan/mt
  • Change: 16.54

Drug Function and Efficacy

This product is a broad-spectrum antifungal drug. Its mechanism is to selectively inhibit squalene epoxidase, which is necessary for the synthesis of ergosterol.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • 関東化学株式会社

    Japan Japan
    Active
  • Tianjin Convinced & Condar Pharmaceutical Co., Ltd.

    China China
    Active
  • Tianjin Yongkang Pharmaceutical Co., Ltd.

    China China
    Active

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