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Benzoic acid

Benzoic acid structure

CAS No:
65-85-0
Formula:
C7H6O2
Chemical Name:
Benzoic acid
Synonyms:
Benzoic acid;Benzenecarboxylic acid;Carboxybenzene;Dracylic acid;Phenylformic acid;Retarder BA;Retardex;Tenn-Plas;Benzeneformic acid;Benzenemethanoic acid;Salvo liquid;Solvo powder;Phenylcarboxylic acid;HA 1;E 210;HA 1 (acid);NSC 149;MENNO-Florades;Purox B;VevoVitall;8013-63-6;331473-08-6;2244876-11-5
Categories:
Cosmetic Ingredient > Cosmetic Preservative

Description

Benzoic Acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.

Benzoic acid Basic Attributes

Molecular Weight：

122.12100

Exact Mass：

122.12

EC Number：

200-618-2

HScode：

4002191900

Characteristics

PSA：

37.30000

XLogP3：

1.3848

Appearance：

White crystals or powder

Density：

1.2659 g/cm³ @ Temp: 15 °C

Melting Point：

122.4 °C

Boiling Point：

249.2 °C @ Press: 760 Torr

Flash Point：

250 °F

Refractive Index：

1.504

Water Solubility：

H2O: Slightly soluble . 0.34 g/100 mL

Storage Conditions：

Ventilated low temperature drying,Separate storage with oxidizing agent

Vapor Pressure：

Vapour pressure, Pa at 25°C: 0.1

Vapor Density：

4.21 (vs air)

Toxicity：

LD50 orally in Rabbit: 1700 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Odor：

Odorless or with a slight benzaldehyde odor

Taste：

ALMOST TASTELESS /BENZOIC ACID USP/

PH：

About 4 (solution in water)

PKA：

4.19(at 25 °C)

Safety Information

Transport codes：

UN 3077 9/PG 3

wgk germany：

hazard class code：

R22; R36/37/38; R42/43

safety instructions：

S26-S45-S37/39-S24-S22-S36/37-S24/25-S23-S53

RTECS Number：

DG0875000

Marks：

Stability/Shelf Life：

Stable. Combustible. Incompatible with strong bases, strong oxidizing agents, alkalies.

Precautionary statement(s)：

P280-P305 + P351 + P338 + P310-P314

Hazard Statements：

H315-H318-H372

Benzoic acid Use and Manufacturing

Methods of Manufacturing

1. Initially by benzoin dry distillation or alkaline hydrolysis in the system can also be obtained from hippuric acid hydrolysis. The industrial production methods of benzoic acid are toluene liquid phase air oxidation, benzyl benzyl trichlorohydrin and phthalic anhydride decarboxylation, while the toluene liquid air oxidation is the most common. Toluene and air into a reactor containing cobalt naphthenate catalyst in the reaction temperature 140-160 ° C, operating pressure 0.2-0.3MPa under the conditions of reaction to generate benzoic acid, by steaming the unreacted toluene was rough Benzoic acid, and then vacuum distillation, recrystallization was finished. The phthalic anhydride decarboxylation method is not easy to refine the final product, and high production costs, only in the small batch of medicine and other products used in the manufacturing process. The product of the chlorination of toluene is not suitable for use in food. Benzoic acid for industrial use, food, medicine and other different specifications. Food grade should be consistent with GB1901-80, content of 99.5% or more, the melting point of 121-123 ℃, and easy oxide, easy carbide, chlorine compounds, burning residue, heavy metals, arsenic content and other quality indicators were provided. Consumption of raw materials fixed: toluene 1140kg / t, cobalt naphthenate 4kg / t. In addition, the production of benzaldehyde from toluene can be a by-product of benzoic acid.2. Although benzoic acid can be obtained by the chlorination of toluene and phthalic acid decarboxylation method, but at home and abroad is widely used in industrial production methods to toluene as raw material liquid catalytic oxidation of air. The catalyst (cobalt acetate, cobalt naphthenate or cobalt acetate) of toluene and air were continuously pumped into the oxidation tower (or kettle), and then 140-165 ℃ and 0.3-0.4MPa pressure oxidation of benzoic acid . The top of the tower tail gas is condensed and activated carbon adsorption method to recover toluene after the venting; tower reactor reaction liquid is often the initial pressure recovery unreacted toluene, benzyl alcohol and benzaldehyde and other light components, and then vacuum distillation of benzoic acid; Toluene and other return oxidation tower, toluene single-pass conversion rate can be controlled at 35% or more. Domestic consumption per ton of benzoic acid toluene 1025-1500kg, cobalt naphthenate about 4kg; foreign toluene consumption of 820kg per ton.3. By benzyl chloride oxidation in crude, washed with cold water, and then recrystallized in hot water.4. The use of hydrolysis and hydrogenation. Hydrolysis: Phthalic anhydride as raw material, by hydrolysis, decarboxylation derived. Chlorination: toluene as raw material, derived by chlorination hydrolysis.5. Tobacco: pOR, 18, 26, 41, 43, 44; FC, 9, 18, 40, 59; BU, 26, 56.

Uses

Keratolytic Mainly used for antifungal and disinfection and antiseptic purposes. Used in the production of medicines, dye carriers, plasticizers, spices and food preservatives, and also used in the performance improvement of alkyd resin coatings; used as intermediates for pharmaceuticals and dyes. Used in the preparation of plasticizers and spices, etc., and also as a rust inhibitor for steel equipment

Computed Properties

Molecular Weight:122.12
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:122.036779430
Monoisotopic Mass:122.036779430
Topological Polar Surface Area:37.3
Heavy Atom Count:9
Complexity:104
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Synthesis Route

90-15-3

Suppliers(298)

104354-87-2

109057-65-0

3375-23-3

3651-02-3

67-66-3

108656-01-5

106124-30-5

Suppliers(1)

65-85-0

Suppliers(2028)

Material

Benzyl alcohol

Toluene

Chlorobenzene

Zinc oxide (ZnO)

Formic acid

Phthalic anhydride

Naphthalene

Downstream Products

Benzyl benzoate

Sodium benzoate

Methyl acrylate

Benzoyl chloride

Price Analysis

Make your Benzoic acid purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Benzoic acid prices .

Data: 2026-05-12
Price: 9100.00Yuan/mt
Change: 800.0

Drug Function and Efficacy

Preservative, has a weak antibacterial effect

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Salicylic Acid Benzoic Acid Pine Oil Liniment
Ingredients	This product is a compound preparation. Each milliliter contains 44 mg of salicylic acid, 60 mg of benzoic acid, and 0.3 ml of pine oil. The auxiliary material is ethanol.
Indication	If you are using other medicines, please consult your physician or pharmacist before using this product.
Specifications	25ml
Manufacturer	Yili Pharmaceutical (Nanning) Co., Ltd.

Salicylic Acid Benzoic Acid Pine Oil Liniment
Ingredients	This product is a compound preparation. Each milliliter contains 44 mg of salicylic acid, 60 mg of benzoic acid, and 0.3 ml of pine oil. The auxiliary material is ethanol.
Indication	If you are using other medicines, please consult your physician or pharmacist before using this product.
Specifications	Compound
Manufacturer	Tangshan Likang Pharmaceutical Co., Ltd.

Jade and Gold Square
Ingredients	Ginseng, seahorse, Polygonum multiflorum, dried extract, Polygonatum sibiricum, dried extract, kiwi juice, dried powder, pig brain powder, procaine hydrochloride, benzoic acid, potassium metabisulfite, vitamin B, vitamin E, tricalcium phosphate, vitamin C
Indication	If you are taking other medicines, please consult your physician or pharmacist before using this product.
Specifications	Each tablet weighs 0.33 grams
Manufacturer	Luoyang Xinchundu Biological Pharmaceutical Co., Ltd.

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Registered Holders

ANMOL CHEMICALS PRIVATE LTD

United States
Active
Sichuan Jinshan Pharmaceutical Co., Ltd.

China
Active
Jilin Aodong BIOTECHNOLOGY Co., Ltd.

China
Active

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